1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin
  3. Vindoline

Vindoline 

Cat. No.: HY-N0687 Purity: 99.33%
Handling Instructions

Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly.

For research use only. We do not sell to patients.

Vindoline Chemical Structure

Vindoline Chemical Structure

CAS No. : 2182-14-1

Size Price Stock Quantity
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
20 mg USD 140 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly[1].

Molecular Weight

456.53

Formula

C₂₅H₃₂N₂O₆

CAS No.

2182-14-1

SMILES

CC[[email protected]@]1(C=CCN2CC3)[[email protected]@]2([H])[[email protected]@]3(C4=CC=C(OC)C=C4N5C)[[email protected]]5([H])[[email protected]](C(OC)=O)(O)[[email protected]@H]1OC(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (547.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1904 mL 10.9522 mL 21.9044 mL
5 mM 0.4381 mL 2.1904 mL 4.3809 mL
10 mM 0.2190 mL 1.0952 mL 2.1904 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6.25 mg/mL (13.69 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 6.25 mg/mL (13.69 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (13.69 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

VindolineMicrotubule/Tubulinvincaalkaloidtubulinself-assemblyInhibitorinhibitorinhibit

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Product Name:
Vindoline
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HY-N0687
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