1. Apoptosis
    Anti-infection
  2. Apoptosis
    Bacterial
    Virus Protease
  3. Lycorine

Lycorine 

Cat. No.: HY-N0288 Purity: >98.0%
Handling Instructions

Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant family with antiviral, antimalarial and antiinflammation activities. Lycorine inhibits the growth and metastasis of hormone-refractory anti-prostate cancer (PCa) and induces cell apoptosis.

For research use only. We do not sell to patients.

Lycorine Chemical Structure

Lycorine Chemical Structure

CAS No. : 476-28-8

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50 mg USD 80 In-stock
Estimated Time of Arrival: December 31
100 mg USD 130 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Lycorine:

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Description

Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant family with antiviral, antimalarial and antiinflammation activities. Lycorine inhibits the growth and metastasis of hormone-refractory anti-prostate cancer (PCa) and induces cell apoptosis[1].

In Vitro

Lycorine inhibits cell proliferation in a dose-dependent manner in the abovementioned 4 PCa cell lines, and the IC50 ranged from 5 μM to 10 μM., it also shows Lycorine has little effects on PNT1A cell's proliferation[1].

Molecular Weight

287.31

Formula

C₁₆H₁₇NO₄

CAS No.

476-28-8

SMILES

O[[email protected]@H]1[[email protected]@H](O)C=C(CC2)[[email protected]@]3([H])N2CC4=C([[email protected]@]31[H])C=C(OCO5)C5=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (87.01 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4806 mL 17.4028 mL 34.8056 mL
5 mM 0.6961 mL 3.4806 mL 6.9611 mL
10 mM 0.3481 mL 1.7403 mL 3.4806 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: >98.0%

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Keywords:

LycorineApoptosisBacterialVirus Proteaseanti-prostate,cancerPCaInhibitorinhibitorinhibit

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Lycorine
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HY-N0288
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