Lycorine hydrochloride monohydrate

Cat. No.: HY-N0288A Purity: 99.23%: Data Sheet
COA

SDS
Handling Instructions
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Lycorine Hydrochloride Monohydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

CAS No. : 6150-58-9

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	Get quote
1 g	Get quote

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Customer Review

Based on 18 publication(s) in Google Scholar

Other Forms of Lycorine hydrochloride monohydrate:

Lycorine In-stock

18 Publications Citing Use of MCE Lycorine hydrochloride monohydrate

Cell Proliferation/Viability Assay

Cell Migration/Invasion Assay

Flow Cytometry

In Vivo Efficacy Study

: Lycorine hydrochloride monohydrate purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2022 Mar 30;41(1):116. [Abstract]; Immunoblot analysis of SCAP protein expression at different concentrations. PLC-SR cells (control) were treated with Lycorine (Ly) (1, 2, 4 μM) alone, Sorafenib (Sora) alone or a combination of Lycorine and Sorafenib (Ly + Sora).

: Lycorine hydrochloride monohydrate purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2022 Mar 30;41(1):116. [Abstract]; The combined use of Lycorine (1, 2, 4 μM) and Sorafenib significantly inhibited the proliferation of PLC-SR cells.

: Lycorine hydrochloride monohydrate purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2022 Mar 30;41(1):116. [Abstract]; Lycorine (1, 2, 4 μM) combined with Sorafenib decelerated the migration and invasion of sorafenib-resistant HCC cells.

: Lycorine hydrochloride monohydrate purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2022 Mar 30;41(1):116. [Abstract]; Flow cytometry analysis indicated that when Lycorine (1, 2, 4 μM) was combined with Sorafenib, the percentage of S phase cells was decreased, and apoptosis was significantly increased.

: Lycorine hydrochloride monohydrate purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2022 Mar 30;41(1):116. [Abstract]; Lycorine (10 mg/kg, i.g.) combined with Sorafenib can reduce the tumor volume in mice.

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Description

Lycorine Hydrochloride Monohydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Molecular Weight

341.79

Formula

C₁₆H₂₀ClNO₅

CAS No.

6150-58-9

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@]2([H])[C@]3([H])N(CCC3=C[C@@H]1O)CC4=CC(OCO5)=C5C=C24.O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL (97.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9258 mL	14.6289 mL	29.2577 mL
5 mM	0.5852 mL	2.9258 mL	5.8515 mL
10 mM	0.2926 mL	1.4629 mL	2.9258 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.23%

Select Batch:

Data Sheet (249 KB) SDS (393 KB)

COA (253 KB) HNMR (125 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.9258 mL	14.6289 mL	29.2577 mL	73.1443 mL
	5 mM	0.5852 mL	2.9258 mL	5.8515 mL	14.6289 mL
	10 mM	0.2926 mL	1.4629 mL	2.9258 mL	7.3144 mL
	15 mM	0.1951 mL	0.9753 mL	1.9505 mL	4.8763 mL
	20 mM	0.1463 mL	0.7314 mL	1.4629 mL	3.6572 mL
	25 mM	0.1170 mL	0.5852 mL	1.1703 mL	2.9258 mL
	30 mM	0.0975 mL	0.4876 mL	0.9753 mL	2.4381 mL
	40 mM	0.0731 mL	0.3657 mL	0.7314 mL	1.8286 mL
	50 mM	0.0585 mL	0.2926 mL	0.5852 mL	1.4629 mL
	60 mM	0.0488 mL	0.2438 mL	0.4876 mL	1.2191 mL
	80 mM	0.0366 mL	0.1829 mL	0.3657 mL	0.9143 mL