1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Cotinine

Cotinine (Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498)

Cat. No.: HY-B1178 Purity: 99.42%
Handling Instructions

Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine, used as a biomarker for exposure to tobacco smoke.

For research use only. We do not sell to patients.

Cotinine Chemical Structure

Cotinine Chemical Structure

CAS No. : 486-56-6

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg USD 88 In-stock
Estimated Time of Arrival: December 31
100 mg USD 150 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine, used as a biomarker for exposure to tobacco smoke.

Clinical Trial
Molecular Weight

176.22

Formula

C₁₀H₁₂N₂O

CAS No.

486-56-6

SMILES

O=C1N(C)[[email protected]](C2=CC=CN=C2)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

Ethanol : 120 mg/mL (680.97 mM; Need ultrasonic)

DMSO : 65 mg/mL (368.86 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.6747 mL 28.3736 mL 56.7472 mL
5 mM 1.1349 mL 5.6747 mL 11.3494 mL
10 mM 0.5675 mL 2.8374 mL 5.6747 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.17 mg/mL (12.31 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.17 mg/mL (12.31 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.17 mg/mL (12.31 mM); Clear solution

*All of the co-solvents are provided by MCE.

Purity: 99.42%

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Cotinine(-)-Cotinine(S)-CotinineNIH-10498NIH10498NIH 10498Endogenous MetaboliteInhibitorinhibitorinhibit

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Product name:
Cotinine
Cat. No.:
HY-B1178
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