2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. Dihydro-β-erythroidine

Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced.

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Dihydro-β-erythroidine Chemical Structure

Dihydro-β-erythroidine Chemical Structure

CAS No. : 23255-54-1

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Dihydro-β-erythroidine Related Antibodies

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Description

Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced[1][2].

In Vivo

Dihydro-β-erythroidine (0.5, 1.6, 5.0 mg/kg; s.c.) blocks the discriminative stimulus properties of nicotine in rats[1].
Dihydro-β-erythroidine (100 ng) shows antagonism of the anxiolytic effect of nicotine in the dorsal raphe´ nucleus in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 200-250 g male hooded Lister rats[1]
Dosage: 0.5, 1.6, 5.0 mg/kg
Administration: S.c.
Result: Prevented the development of CTAs (conditioned taste aversion) and blocked the discriminative stimulus effect of nicotine (0.2 or 0.4 mg/kg SC) for 45 min after its administration.
Molecular Weight

275.34

Formula

C16H21NO3
CAS No.
SMILES

CO[C@H]1CC=C2CCN3CCC4=C([C@@]32C1)CC(OC4)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Dihydro-β-erythroidine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihydro-β-erythroidine23255-54-1nAChRNicotinic acetylcholine receptorsnicotineanxiolyticInhibitorinhibitorinhibit

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