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R-(+)-Cotinine (Synonyms: (+)-Cotinine; (R)-Cotinine; (R)-NIH-10498)

Cat. No.: HY-B1178A
Handling Instructions

R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs.

For research use only. We do not sell to patients.

R-(+)-Cotinine Chemical Structure

R-(+)-Cotinine Chemical Structure

CAS No. : 32162-64-4

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Description

R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs[1].

In Vitro

R-(+)-Cotinine (1 μM) significantly enhances the Ach (40 μM)-evoked current in human α7 nAChRs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

R-(+)-Cotinine (0.3-10 mg/kg; a single i.p.) enhances the effects of a subthreshold dose of Donepezil (0.5 mg/kg) on novel object recognition (NOR) performance[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

176.22

Formula

C₁₀H₁₂N₂O

CAS No.
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Please store the product under the recommended conditions in the Certificate of Analysis.

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R-(+)-Cotinine
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HY-B1178A
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