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Maleimide 

Cat. No.: HY-W007324 Purity: >98.0%
Handling Instructions

Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes.

For research use only. We do not sell to patients.

Maleimide Chemical Structure

Maleimide Chemical Structure

CAS No. : 541-59-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes[1][2].

Molecular Weight

97.07

Formula

C₄H₃NO₂

CAS No.

541-59-3

SMILES

O=C(N1)C=CC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (1030.18 mM)

H2O : 50 mg/mL (515.09 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.3018 mL 51.5092 mL 103.0184 mL
5 mM 2.0604 mL 10.3018 mL 20.6037 mL
10 mM 1.0302 mL 5.1509 mL 10.3018 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (25.75 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (25.75 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (25.75 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >98.0%

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

MaleimideOthersantibody-drugconjugateADCcancerfluorogenicprobeInhibitorinhibitorinhibit

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Product Name:
Maleimide
Cat. No.:
HY-W007324
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