541-59-3
541-59-3
Chemical Structure
Maleimide
- CAS 番号: 541-59-3
- Formula:C4H3NO2
- Molecular Weight:97.07
IUPAC Name: 1H-pyrrole-2,5-dione
InChIKey: PEEHTFAAVSWFBL-UHFFFAOYSA-N
SMILES: O=C(N1)C=CC1=O
Biological Activity: Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes[1][2].
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Maleimide | 99.90% | Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes. | ||||||||||||||||||||
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Maleimide (Standard) | ≥98% | Maleimide (Standard) is the analytical standard of Maleimide (HY-W007324). This product is intended for research and analytical applications. Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.77
HY-W026277N-Methylmaleimide -
Similarity Score 0.77
HY-W023557Citraconimide -
Similarity Score 0.76
HY-W0767943-Bromo-1H-pyrrole-2,5-dione -
Similarity Score 0.74
HY-D0843RN-Ethylmaleimide (Standard) -
Similarity Score 0.73
HY-41877Succinimide -
Similarity Score 0.73
HY-41877SSuccinimide-15N -
Similarity Score 0.73
HY-W699500N-Maleimidomethanol -
Similarity Score 0.72
HY-W010612Hydantoin -
Similarity Score 0.72
HY-W777501Imidazolidine-2,4-dione-13C,15N -
Explore the MedChemAI to find more analogs
References
- [1]. Renault K, et, al. Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies. Bioconjug Chem. 2018 Aug 15;29(8):2497-2513. [Content Brief]
- [2]. Zhang S, et, al. A Maleimide-functionalized Tetraphenylethene for Measuring and Imaging Unfolded Proteins in Cells. Chem Asian J. 2019 Mar 15;14(6):904-909. [Content Brief]
