N-Methylmaleimide
Based on 1 Customer Validation
N-Methylmaleimide (1-Methyl-1H-pyrrole-2,5-dione) is an electron-deficient alkene that can be used as a thiol blocking agent.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.92%
- CAS 番号: 930-88-1
- 分子式: C5H5NO2
- 分子量:111.10
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保管条件:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | GI50 |
>10 μg/mL
Compound: 44
|
Cytotoxicity against human MCF7 cells assessed as cell growth after 2 days by sulforhodamine B assay
Cytotoxicity against human MCF7 cells assessed as cell growth after 2 days by sulforhodamine B assay
|
[PMID: 21481593] |
| NCI-H460 | GI50 |
>10 μg/mL
Compound: 44
|
Cytotoxicity against human H460 cells assessed as cell growth after 2 days by sulforhodamine B assay
Cytotoxicity against human H460 cells assessed as cell growth after 2 days by sulforhodamine B assay
|
[PMID: 21481593] |
| SF-268 | GI50 |
>10 μg/mL
Compound: 44
|
Cytotoxicity against human SF268 cells assessed as cell growth after 2 days by sulforhodamine B assay
Cytotoxicity against human SF268 cells assessed as cell growth after 2 days by sulforhodamine B assay
|
[PMID: 21481593] |
化学情報
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CAS 番号 930-88-1
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性状 Solid
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分子量 111.10
-
分子式 C5H5NO2
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Color Off-white to yellow
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SMILES
O=C(N1C)C=CC1=O
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別名
1-Methyl-1H-pyrrole-2,5-dione
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (900.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.0009 mL | 45.0045 mL | 90.0090 mL | 225.0225 mL |
| 5 mM | 1.8002 mL | 9.0009 mL | 18.0018 mL | 45.0045 mL | |
| 10 mM | 0.9001 mL | 4.5005 mL | 9.0009 mL | 22.5023 mL | |
| 15 mM | 0.6001 mL | 3.0003 mL | 6.0006 mL | 15.0015 mL | |
| 20 mM | 0.4500 mL | 2.2502 mL | 4.5005 mL | 11.2511 mL | |
| 25 mM | 0.3600 mL | 1.8002 mL | 3.6004 mL | 9.0009 mL | |
| 30 mM | 0.3000 mL | 1.5002 mL | 3.0003 mL | 7.5008 mL | |
| 40 mM | 0.2250 mL | 1.1251 mL | 2.2502 mL | 5.6256 mL | |
| 50 mM | 0.1800 mL | 0.9001 mL | 1.8002 mL | 4.5005 mL | |
| 60 mM | 0.1500 mL | 0.7501 mL | 1.5002 mL | 3.7504 mL | |
| 80 mM | 0.1125 mL | 0.5626 mL | 1.1251 mL | 2.8128 mL | |
| 100 mM | 0.0900 mL | 0.4500 mL | 0.9001 mL | 2.2502 mL |