1. Acids and Aldehydes

Kainic acid 

Cat. No.: HY-N2309 Purity: >99.0%
Handling Instructions

Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS.

For research use only. We do not sell to patients.

Kainic acid Chemical Structure

Kainic acid Chemical Structure

CAS No. : 487-79-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 164 In-stock
Estimated Time of Arrival: December 31
1 mg USD 70 In-stock
Estimated Time of Arrival: December 31
5 mg USD 140 In-stock
Estimated Time of Arrival: December 31
10 mg USD 195 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS.

In Vivo

Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. HO-I levels are significantly enhanced one, three and seven days after i.c.v, injection of Kainic acid. One day after i.c.v, injection of Kainic acid, the HO-I protein level reaches a maximum and then decreases, but is still significantly enhanced versus the vehicle-injected group. After i.c.v. injection of Kainic acid, HO-I-immunoreactivity is strongly induced not only in the CA3 but also widely in the whole hippocampus[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6898 mL 23.4489 mL 46.8977 mL
5 mM 0.9380 mL 4.6898 mL 9.3795 mL
10 mM 0.4690 mL 2.3449 mL 4.6898 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Animal Administration
[1]

The rats are fasted over night with free access to water. For stereotaxic injection, rats are anaesthetized (sodium pentobarbital, 50 mg/kg, i.p.) and immobilized in a Kopf stereotaxic frame. The rats are microinjected with 1 μg Kainic acid in 2 μL of sterilized physiological saline into the right lateral ventricle, i.e., 0.2 mm caudal from the bregma, 1.2 mm right lateral and 3.8 mm ventral according to the rat brain atlas. For control, rats are injected with same amount (2 μL) of vehicle, sterilized physiological saline. Five rats in each group are used in this study[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

213.23

Formula

C₁₀H₁₅NO₄

CAS No.

487-79-6

SMILES

O=C(O)C[[email protected]@H]1[[email protected]@H](C(O)=O)NC[[email protected]@H]1C(C)=C

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: >99.0%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Kainic acid
Cat. No.:
HY-N2309
Quantity:

Kainic acid

Cat. No.: HY-N2309