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Cat. No.: HY-N3849

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Ervamycine

Ervamycine (compound III) is a natural alkaloid compound.

For research use only. We do not sell to patients.

CAS No.: 27773-39-3
Formula: C₂₂H₂₆N₂O₃
Molecular Weight:366.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Ervamycine Chemical Structure

CAS No.: 27773-39-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Ervamycine (compound III) is a natural alkaloid compound^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	12.8 μM Compound: 8	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 20462230]
A549	IC₅₀	12.8 μmol Compound: 8	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 20462230]
A549	IC₅₀	1 μM Compound: 11	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 22260257]
HL-60	IC₅₀	0.2 μM Compound: 8	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 20462230]
HL-60	IC₅₀	0.2 μmol Compound: 8	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 20462230]
HL-60	IC₅₀	0.5 μM Compound: 11	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 22260257]
MCF7	IC₅₀	2.1 μM Compound: 8	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 20462230]
MCF7	IC₅₀	2.1 μmol Compound: 8	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 20462230]
MCF7	IC₅₀	0.2 μM Compound: 11	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 22260257]
SMMC-7721	IC₅₀	13.1 μM Compound: 8	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 20462230]
SMMC-7721	IC₅₀	13.1 μmol Compound: 8	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 20462230]
SMMC-7721	IC₅₀	1.1 μM Compound: 11	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 22260257]
SW480	IC₅₀	12.7 μM Compound: 8	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 20462230]
SW480	IC₅₀	12.7 μmol Compound: 8	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 20462230]
SW480	IC₅₀	2.4 μM Compound: 11	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 22260257]

Chemical Information

CAS No. 27773-39-3
Molecular Weight 366.45
Formula C₂₂H₂₆N₂O₃
SMILES

CC[C@@]12[C@@]3([H])[C@]4(CCN3CC=C2)C(NC5=CC(OC)=CC=C45)=C(C(OC)=O)C1
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pyuskyulev, B., et al. Further studies on alkaloids from Vinca herbacea W. K. Collect. Czech. Chem. Commun. 1967, 32, 1289-1294.

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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