1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. 5-HT Receptor
  4. 5-HT5 Receptor Inhibitors

5-HT5 Receptor Inhibitors

5-HT1 Receptor

5-HT2 Receptor

5-HT3 Receptor

5-HT5 Receptor

5-HT6 Receptor

5-HT7 Receptor

5-HT Receptor

5-HT4 Receptor

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform 5-HT5 Receptor together.

Please try each isoform separately.

5-HT5 Receptor Specific Agonists & Antagonists
Product Name 5-HT5 Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT5 Receptor Selectivity Purity
Methiothepin mesylate
5-HT5A Receptor, pKd: 7.0
5-HT5B Receptor, pKd: 7.8
5-HT1A Receptor, pKd: 7.10
5-HT1B Receptor, pKd: 7.28
5-HT1C Receptor, pKd: 7.56
5-HT1D Receptor, pKd: 6.99
5-HT2A Receptor, pKi: 8.50
5-HT2B Receptor, pKi: 8.68
5-HT2C Receptor, pKi: 8.35
 
5-HT6 Receptor, pKd: 8.74
5-HT7 Receptor, pKd: 8.99
Pan Antagonist 99.32%
RS-127445 hydrochloride
5-HT5 Receptor, pKi: <6
 
5-HT2A Receptor, pKi: 6.3
5-HT2C Receptor, pKi: 6.4
5-HT2B Receptor, pKi: 9.5
5-HT3 Receptor, pKi: <6
5-HT6 Receptor, pKi: <6
  Pan Antagonist 99.68%
Asenapine
5-HT5 Receptor, pKi: 8.8
5-HT1A Receptor, pKi: 8.6
5-HT1B Receptor, pKi: 8.4
5-HT2A Receptor, pKi: 10.2
5-HT2C Receptor, pKi: 10.5
5-HT2B Receptor, pKi: 9.8
 
5-HT6 Receptor, pKi: 9.6
5-HT7 Receptor, pKi: 9.9
Pan Antagonist 98.81%
AS19
5-HT5 Receptor, Ki: 98.5 nM
5-HT1A Receptor, Ki: 89.7 nM
5-HT1B Receptor, Ki: 490 nM
5-HT1D Receptor, Ki: 6.6 nM
     
Human 5-HT7 Receptor , IC50: 0.83 nM
Human 5-HT7 Receptor , Ki: 0.6 nM
Pan Agonist >99.0%
5-Carboxamidotryptamine maleate
5-HT5 Receptor
5-HT1A Receptor
5-HT1B Receptor
5-HT1D Receptor
     
5-HT7 Receptor
Pan Agonist
AP521
5-HT5A Receptor, IC50: 422 nM (in human)
5-HT1A Receptor, IC50: 94 nM (in human)
5-HT1A Receptor, IC50: 135 nM (in rat)
5-HT1B Receptor, IC50: 254 nM (in rat)
5-HT1B Receptor, IC50: 5530 nM (in human)
5-HT1D Receptor, IC50: 418 nM (in human)
     
5-HT7 Receptor, IC50: 198 nM (in rat)
Pan Agonist