1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. 5-HT Receptor
  4. 5-HT3 Receptor Isoform

5-HT3 Receptor

 

5-HT3 Receptor Related Products (63):

Cat. No. Product Name Effect Purity
  • HY-14564A
    GTS-21 dihydrochloride
    Antagonist 99.92%
    GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti‑inflammatory and cognition‑enhancing activities.
  • HY-14541
    Olanzapine
    Antagonist 99.89%
    Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM).
  • HY-15414
    Vortioxetine
    Inhibitor 99.52%
    Vortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
  • HY-B0002B
    Ondansetron
    Antagonist 99.46%
    Ondansetron(GR 38032; SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.
  • HY-15414A
    Vortioxetine hydrobromide
    Inhibitor 99.91%
    Vortioxetine hydrobromide is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
  • HY-148038
    5-HT3 antagonist 5
    Antagonist 99.75%
    5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT3 receptor antagonist.
  • HY-B0352
    Mirtazapine
    Antagonist 99.97%
    Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent.
  • HY-15419
    RS-127445 hydrochloride
    Antagonist 99.58%
    RS-127445 hydrochloride is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist with a pKi of 9.5.
  • HY-A0021
    Palonosetron hydrochloride
    Antagonist 99.94%
    Palonosetron hydrochloride is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
  • HY-19358
    2-Methyl-5-HT
    Agonist 98.73%
    2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist.
  • HY-70050C
    Alosetron Hydrochloride
    Antagonist 99.79%
    Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist.
  • HY-B0068
    Azasetron hydrochloride
    Antagonist 99.78%
    Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist.
  • HY-B0002A
    Ondansetron hydrochloride dihydrate
    Antagonist 99.03%
    Ondansetron (GR 38032) hydrochloride dehydrate is an orally active, highly selective and competitive 5-HT3 receptor antagonist (crosses the blood-brain barrier).
  • HY-103152
    GR 113808
    Antagonist 99.44%
    GR 113808 is a potent and highly selective 5-HT4 receptor antagonist (pKb= 8.8).
  • HY-B0071A
    Granisetron Hydrochloride
    Antagonist 99.90%
    Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
  • HY-B0020
    Tropisetron Hydrochloride
    Antagonist 99.95%
    Tropisetron Hydrochloride (SDZ-ICS-930) is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
  • HY-19650
    Pumosetrag Hydrochloride
    Agonist 99.77%
    Pumosetrag Hydrochloride (MKC-733; DDP-733) is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
  • HY-32329
    Setiptiline
    Modulator 98.04%
    Setiptiline (Org-8282) is a serotonin receptor antagonist.
  • HY-A0008
    Talipexole dihydrochloride
    Antagonist 99.88%
    Talipexole dihydrochloride (B-HT 920 dihydrochloride) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays antiParkinsonian activity.
  • HY-32329A
    Setiptiline maleate
    Antagonist 98.18%
    Setiptiline maleate (MO-8282 maleate) is a serotonin receptor antagonist.