1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. 5-HT Receptor
  4. 5-HT Receptor Inhibitors

5-HT Receptor Inhibitors

5-HT1 Receptor

5-HT2 Receptor

5-HT3 Receptor

5-HT4 Receptor

5-HT5 Receptor

5-HT6 Receptor

5-HT7 Receptor

5-HT Receptor

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

5-HT Receptor Inhibitors, Agonists, Antagonists & Modulators
Product Name 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor Purity
Puerarin  
5-HT2C Receptor
            99.20%
Harmine  
5-HT2A Receptor, Ki: 397 nM
            99.93%
SCH-23390 hydrochloride  
5-HT2C Receptor, Ki: 9.3 nM
            99.91%
Clozapine  
5-HT2A Receptor, Ki: 4 nM (Inhibitor)
            99.99%
Olanzapine
5-HT1 Receptor, Ki: 7 nM
5-HT2A Receptor, Ki: 4 nM
5-HT2C Receptor, Ki: 11 nM
5-HT3 Receptor, Ki: 57 nM
   
5-HT6 Receptor, Ki: 5 nM
    99.89%
GTS-21 dihydrochloride    
5-HT3A Receptor, IC50: 3.1 μM
          99.92%
SB-269970 hydrochloride            
5-HT7 Receptor, pKi: 8.3
  99.15%
Risperidone  
5-HT2A Receptor, Ki: 4.8 nM
            98.01%
Brexpiprazole
5-HT1A Receptor, Ki: 0.12 nM
5-HT2A Receptor, Ki: 0.47 nM
            99.64%
8-OH-DPAT
5-HT1A Receptor, pIC50: 8.19
         
5-HT7 Receptor, Ki: 466 nM
  98.18%
Thioridazine hydrochloride              
serotonin
99.96%
Volinanserin  
5-HT2 Receptor, Ki: 0.36 nM
            98.33%
SEP-363856 hydrochloride
5-HT1A Receptor, EC50: 2.3 μM
5-HT1B Receptor, EC50: 15.6 μM
5-HT1D Receptor, EC50: 0.262 μM
5-HT2A Receptor, EC50: >10 μM
5-HT2C Receptor, EC50: 30 μM
       
5-HT7 Receptor, EC50: 6.7 μM
  99.78%
Amitriptyline hydrochloride
5-HT1A Receptor, IC50: 450 nM
5-HT1B Receptor, IC50: 40 nM
5-HT2A Receptor, IC50: 4 nM
5-HT2B Receptor, IC50: 40 nM
5-HT2C Receptor, IC50: 6 nM
            99.56%
Pimavanserin hemitartrate  
5-HT2A Receptor, pIC50: 8.73
5-HT2A Receptor, pKi: 9.3
            99.75%
Ketanserin  
5-HT2 Receptor
            99.24%
Aripiprazole
5-HT1A Receptor, Ki: 4.2 nM
              99.93%
SB 242084  
5-HT2C Receptor, pKi: 9.0
            99.84%
Quetiapine
5-HT1A Receptor, pKi: 5.74
5-HT1A Receptor, pEC50: 4.77
5-HT2A Receptor, pKi: 7.54
5-HT2C Receptor, pKi: 5.55
            99.96%
Cisapride      
5-HT4 Receptor, EC50: 0.14 μM
        99.72%
Lurasidone
5-HT1A Receptor, IC50: 6.75 nM
         
5-HT7 Receptor, IC50: 0.495 nM
  99.90%
Vortioxetine    
5-HT3A Receptor, Ki: 3.7 nM
     
Human 5-HT7 Receptor , Ki: 19 nM
  99.52%
Pimavanserin  
5-HT2A Receptor, pIC50: 8.7
            99.78%
Pindolol
5-HT1A Receptor
              99.91%
Vortioxetine hydrobromide    
5-HT3A Receptor, Ki: 3.7 nM
     
5-HT7 Receptor, Ki: 19 nM
  99.91%
Ondansetron    
5-HT3 Receptor
          99.46%
Nuciferine
5-HT1A Receptor, EC50: 3.2 μM
5-HT2C Receptor, IC50: 131 nM
5-HT2A Receptor, IC50: 478 nM
5-HT2B Receptor, IC50: 1 μM
     
5-HT6 Receptor, EC50: 700 nM
5-HT7 Receptor, IC50: 150 nM
  99.46%
Ritanserin  
5-HT2 Receptor, IC50: 0.9 nM
            99.78%
Perphenazine
5-HT1A Receptor, Ki: 421 nM
5-HT2A Receptor, Ki: 5.6 nM
     
5-HT6 Receptor, Ki: 17 nM
5-HT7 Receptor, Ki: 23 nM
  99.72%
Sertindole  
5-HT2A Receptor
5-HT2C Receptor
            99.75%
Ketanserin tartrate  
5-HT2 Receptor
            99.99%
Piboserod      
5-HT4 Receptor
        99.12%
SB-224289 hydrochloride
5-HT1B Receptor
              ≥99.0%
SKF-83566  
5-HT2 Receptor, Ki: 11 nM
            99.86%
Tegaserod maleate  
5-HT2B Receptor (Antagonist)
 
5-HT4 Receptor (Agonist)
        99.75%
Alprenolol
5-HT1A Receptor
              99.87%
Methiothepin mesylate
5-HT1A Receptor, pKd: 7.10
5-HT1B Receptor, pKd: 7.28
5-HT1C Receptor, pKd: 7.56
5-HT1D Receptor, pKd: 6.99
5-HT2A Receptor, pKi: 8.50
5-HT2B Receptor, pKi: 8.68
5-HT2C Receptor, pKi: 8.35
   
5-HT5A Receptor, pKd: 7.0
5-HT5B Receptor, pKd: 7.8
5-HT6 Receptor, pKd: 8.74
5-HT7 Receptor, pKd: 8.99
  99.32%
Cyproheptadine hydrochloride  
5-HT2 Receptor
            99.98%
LP-211
5-HT1A Receptor, Ki: 188 nM
         
5-HT7 Receptor, Ki: 0.58 nM
  99.61%
Ziprasidone
Rat 5-HT1A Receptor, Ki: 3.4 nM
human 5-HT1A Receptor, Ki: 2.5 nM
Rat 5-HT2A, Ki: 0.42 nM
            98.28%
Mosapride citrate      
5-HT4 Receptor
        99.80%
Tandospirone
5-HT1A Receptor, Ki: 27 nM
              99.41%
Nefazodone hydrochloride  
5-HT2A Receptor, Ki: 5.8 nM
            99.02%
Perospirone
5-HT1A Receptor, Ki: 2.9 nM
5-HT1 Receptor, Ki: 18 nM
5-HT2A Receptor, Ki: 0.6 nM
            99.43%
Paliperidone  
5-HT2A Receptor
            99.69%
Palonosetron hydrochloride    
5-HT3 Receptor
          99.94%
Vilazodone
5-HT1A Receptor
              99.84%
Trimipramine maleate  
5-HT2 Receptor, pKi: 8.10
            99.97%
Lumateperone tosylate  
5-HT2A Receptor, Ki: 0.54 nM
            99.42%
Alprenolol hydrochloride
5-HT1A Receptor
              99.78%
Gamma-Mangostin  
5-HT2A Receptor
            99.90%
RS-127445 hydrochloride  
5-HT2A Receptor, pKi: 6.3
5-HT2C Receptor, pKi: 6.4
5-HT2B Receptor, pKi: 9.5
5-HT3 Receptor, pKi: <6
 
5-HT5 Receptor, pKi: <6
5-HT6 Receptor, pKi: <6
    99.58%
Cariprazine
5-HT1A Receptor, Ki: 2.6 nM
              99.35%
Cariprazine hydrochloride
5-HT1A Receptor, Ki: 2.6 nM
              99.89%
Lurasidone Hydrochloride
5-HT1A Receptor, IC50: 6.75 nM
         
5-HT7 Receptor, IC50: 0.495 nM
  99.96%
Mirtazapine  
5-HT2 Receptor, pKi: 8.05
5-HT3 Receptor, pKi: 8.1
          99.97%
Paliperidone palmitate  
5-HT2A Receptor
            98.41%
Sumatriptan succinate
5-HT1D Receptor, Ki: 17 nM
5-HT1B Receptor, Ki: 27 nM
5-HT1A Receptor, Ki: 100 nM
              99.97%
Alosetron Hydrochloride    
5-HT3 Receptor
          99.79%
Prucalopride      
5-HT4A Receptor, pKi: 8.6
5-HT4B Receptor, pKi: 8.1
        99.83%
R 59-022              
serotonin
99.82%
Vabicaserin hydrochloride  
5-HT2C Receptor, EC50: 8 nM
            99.92%
Sarpogrelate hydrochloride  
5-HT2A Receptor, pKi: 8.52
5-HT2B Receptor, pKi: 6.57
5-HT2C Receptor, pKi: 7.43
            99.45%
(Z)-Thiothixene              
serotonin
99.76%
Xanthotoxol              
serotonin
99.58%
Roluperidone  
5-HT2A Receptor, Ki: 7.53 nM
            99.91%
Vilazodone Hydrochloride
5-HT1A Receptor
              99.90%
SB 242084 dihydrochloride  
5-HT2C Receptor, pKi: 9.0
            98.33%
RU 24969
5-HT1B Receptor, Ki: 0.38 nM
5-HT1A Receptor, Ki: 2.5 nM
              99.97%
Loxapine  
human 5-HT2
            99.69%
SB 243213
human 5-HT1A Receptor, pKi: <5.3
human 5-HT1B Receptor, pKi: 5.5
human 5-HT1D Receptor, pKi: 6.32
human 5-HT1E Receptor, pKi: <5.4
human 5-HT1F Receptor, pKi: 5.35
Human 5-HT2C Receptor, pKi: 9.37
Human 5-HT2A Receptor, pKi: 7.01
human 5-HT2B Receptor, pKi: 7.2
     
Human 5-HT6 Receptor, pKi: 6.5
Human 5-HT7 Receptor , pKi: 5.64
  98.62%
Syk Inhibitor II              
serotonin, IC50: 460 nM
98.05%
2-Methyl-5-HT    
5-HT3 Receptor
          98.73%
Asenapine
5-HT1A Receptor, pKi: 8.6
5-HT1B Receptor, pKi: 8.4
5-HT2A Receptor, pKi: 10.2
5-HT2C Receptor, pKi: 10.5
5-HT2B Receptor, pKi: 9.8
   
5-HT5 Receptor, pKi: 8.8
5-HT6 Receptor, pKi: 9.6
5-HT7 Receptor, pKi: 9.9
  99.93%
Azasetron hydrochloride    
5-HT3 Receptor, IC50: 0.33 nM
          99.78%
Metergoline  
5-HT2A Receptor, pKi: 8.64
5-HT2B Receptor, pKi: 8.75
5-HT2C Receptor, pKi: 8.75
       
Human 5-HT7 Receptor , Ki: 16 nM
  99.88%
Flibanserin
5-HT1A Receptor, Ki: 1 nM
5-HT2A Receptor, Ki: 49 nM
            99.10%
Piromelatine
5-HT1A Receptor (Agonist)
5-HT1D Receptor (Agonist)
5-HT2B Receptor (Antagonist)
            99.21%
Oxatomide              
serotonin
99.47%
Rotigotine
5-HT1A Receptor, Ki: 30 nM
         
5-HT7 Receptor, Ki: 86 nM
  99.98%
Agomelatine  
5-HT2C Receptor, pKi: 6.4 (native porcine)
5-HT2C Receptor, pKi: 6.2 (human)
            98.77%
Granisetron Hydrochloride    
5-HT3 Receptor, IC50: 17 μM
          99.90%
Eletriptan hydrobromide
5-HT1B Receptor, Ki: 0.92 nM
5-HT1D Receptor, Ki: 3.14 nM
              98.13%
PCPA methyl ester hydrochloride              
serotonin
99.89%
SB-277011 hydrochloride
5-HT1D Receptor
5-HT1B Receptor
              98.22%
Harmine hydrochloride  
5-HT2A Receptor, Ki: 397 nM
            98.79%
LY310762
5-HT1D Receptor, Ki: 249 nM
              99.84%
Pizotifen  
5-HT2A Receptor
            99.73%
Blonanserin  
5-HT2A Receptor, Ki: 0.812 nM
5-HT2C Receptor, Ki: 26.4 nM
     
5-HT6 Receptor, Ki: 11.7 nM
    98.73%
Idalopirdine Hydrochloride          
5-HT6 Receptor, Ki: 0.83 nM
    99.83%
Tropisetron Hydrochloride    
5-HT3 Receptor, IC50: 70.1 nM
          99.95%
Ondansetron hydrochloride dihydrate    
5-HT3 Receptor
          99.03%
BRL-15572 dihydrochloride
5-HT1D Receptor
              99.77%
Spiperone hydrochloride
5-HT1A Receptor, Ki: 49 nM
5-HT2A Receptor, Ki: 1 nM
            99.10%
p-MPPI hydrochloride
5-HT1A Receptor
              99.19%
GR 113808
5-HT1A Receptor
5-HT2A Receptor
5-HT2C Receptor
5-HT3 Receptor
5-HT4 Receptor
        99.44%
Rotigotine Hydrochloride
5-HT1A Receptor, Ki: 30 nM
         
5-HT7 Receptor, Ki: 86 nM
  99.65%
Intepirdine          
5-HT6 Receptor, pKi: 9.63
    98.92%
Asenapine maleate  
5-HT2A Receptor, Ki: 0.06 nM
5-HT2C Receptor, Ki: 0.03 nM
       
5-HT7 Receptor, Ki: 0.13 nM
  99.95%
Iloperidone
Rat 5-HT1A Receptor, Ki: 168 nM
Rat 5-HT2 Receptor, Ki: 3.1 nM
Human 5-HT2A Receptor, Ki: 5.6 nM
Human 5-HT2C Receptor, Ki: 42.8 nM
     
Rat 5-HT6 Receptor, Ki: 42.7 μM
Rat 5-HT7 Receptor, Ki: 21.6 nM
  99.95%
Pumosetrag Hydrochloride    
5-HT3 Receptor
          99.77%
NAN-190 hydrobromide
5-HT1 Receptor
              98.59%
Fananserin  
5-HT2 Receptor, Ki: 0.37 nM
            99.97%
SB 204741  
human 5-HT2B Receptor, pKi: 7.1
            99.91%
Asenapine hydrochloride  
5-HT2A Receptor, Ki: 0.06 nM
5-HT2C Receptor, Ki: 0.03 nM
       
5-HT7 Receptor, Ki: 0.13 nM
  98.76%
Alverine citrate
5-HT1A Receptor, IC50: 101 nM
              99.43%
Nelotanserin  
5-HT2A Receptor, IC50: 1.7 nM
5-HT2C Receptor, IC50: 79 nM
5-HT2B Receptor, IC50: 791 nM
            99.79%
Rotundine
5-HT1A Receptor, IC50: 370 nM
              99.39%
AS19
5-HT1A Receptor, Ki: 89.7 nM
5-HT1B Receptor, Ki: 490 nM
5-HT1D Receptor, Ki: 6.6 nM
     
5-HT5 Receptor, Ki: 98.5 nM
 
Human 5-HT7 Receptor , IC50: 0.83 nM
Human 5-HT7 Receptor , Ki: 0.6 nM
  99.78%
Eptapirone
5-HT1A Receptor
              99.91%
SB-399885 hydrochloride          
5-HT6 Receptor
    99.54%
Arotinolol  
5-HT2A Receptor
            98.23%
SB 258719            
5-HT7 Receptor, pKi: 7.5
  99.16%
Adoprazine
5-HT1A Receptor, pEC50: 9
5-HT1A Receptor, pKi: 9.1
         
5-HT7 Receptor, pKi: 7.2
  98.10%
Prucalopride succinate      
5-HT4A Receptor, pKi: 8.6
5-HT4B Receptor, pKi: 8.1
        99.83%
Talipexole dihydrochloride    
5-HT3 Receptor
          99.88%
Setiptiline maleate  
5-HT2A Receptor
5-HT2C Receptor
5-HT3 Receptor
          98.18%
Loxapine succinate  
human 5-HT2
            99.81%
Ziprasidone hydrochloride monohydrate
Rat 5-HT1A Receptor, Ki: 3.4 nM
Rat 5-HT2A, Ki: 0.42 nM
            99.74%
Ansofaxine hydrochloride              
serotonin, IC50: 723 nM
99.87%
Xaliproden hydrochloride
5-HT1A Receptor, IC50: 3 nM
              99.05%
Pipamperone
5-HT1 Receptor, pKi: 5.7
5-HT2A Receptor, pKi: 8.2
5-HT2C Receptor, pKi: 6.9
            99.89%
Almotriptan malate
5-HT1B Receptor
5-HT1D Receptor
              99.91%
Spiramide
5-HT1A Receptor, Ki: 50 nM
5-HT1C Receptor, Ki: 4300 nM
5-HT2 Receptor, Ki: 2 nM
            98.81%
SB 271046 Hydrochloride
5-HT1D Receptor, pKi: 6.55
5-HT1A Receptor, pKi: 6.35
5-HT1B Receptor, pKi: 6.05
5-HT1F Receptor, pKi: 5.95
5-HT1E Receptor, pKi: <4.99
5-HT2A Receptor, pKi: 5.62
5-HT2B Receptor, pKi: 5.41
Human 5-HT2C Receptor, pKi: 5.73
 
5-HT4 Receptor, pKi: 5.27
 
5-HT6 Receptor, pKi: 8.92-9.02
5-HT7 Receptor, pKi: 5.39
  98.64%
BRL 54443
5-HT1E Receptor, Ki: 1.1 nM
5-HT1F Receptor, Ki: 0.7 nM
5-HT1A Receptor, Ki: 63 nM
5-HT1B Receptor, Ki: 126 nM
5-HT1D Receptor, Ki: 63 nM
5-HT2A Receptor, Ki: 1259 nM
5-HT2B Receptor, Ki: 100 nM
5-HT2C Receptor, Ki: 316 nM
     
5-HT6 Receptor, Ki: >10,000 nM
5-HT7 Receptor, Ki: >10,000 nM
  99.89%
LY334370
5-HT1F Receptor, Ki: 1.6 nM
              99.80%
PRX-08066  
5-HT2B Receptor, IC50: 3.4 nM
           
WAY-181187          
5-HT6 Receptor, Ki: 2.2 nM
5-HT6 Receptor, EC50: 6.6 nM
    98.05%
JNJ-18038683            
Rat 5-HT7 Receptor, pKi: 8.19 (in HEK293 cells )
Human 5-HT7 Receptor , pKi: 8.20 (in HEK293 cells )
  99.76%
Cinanserin hydrochloride  
5-HT2 Receptor, Ki: 41 nM
            99.74%
Donitriptan
5-HT1B Receptor, pKi: 9.4
5-HT1D Receptor, pKi: 9.3
              98.12%
Ocaperidone
5-HT1A Receptor, pEC50: 7.6 (h5-HT1A)
5-HT1A Receptor, pKi: 8.08 (h5-HT1A)
5-HT2 Receptor, Ki: 0.14 nM
            99.63%
Phenylbiguanide    
5-HT3 Receptor, EC50: 3 μM
          ≥98.0%
Geissoschizine methyl ether
5-HT1A Receptor
              ≥98.0%
Flumexadol  
5-HT2C Receptor, Ki: 25 nM
            98.87%
Flesinoxan
5-HT1A Receptor, EC50: 24 nM
              99.07%
OPC-14523 hydrochloride
5-HT1A Receptor, IC50: 2.3 nM
              99.90%
SB-616234-A
5-HT1B Receptor
              98.14%
Tianeptine sodium salt              
serotonin
99.82%
CP-809101 hydrochloride  
5-HT2C Receptor, pEC50: 9.96
5-HT2B Receptor, pEC50: 7.19
5-HT2A Receptor, pEC50: 6.81
            99.83%
Setiptiline  
5-HT2A Receptor
5-HT2C Receptor
5-HT3 Receptor
          98.04%
Ramosetron Hydrochloride    
5-HT3 Receptor
          99.91%
Naftidrofuryl oxalate  
5-HT2 Receptor
            98.39%
Dolasetron    
5-HT3 Receptor
          ≥98.0%
LY 344864
human 5-HT1F Receptor, Ki: 0.006 μM
human 5-HT1A Receptor, Ki: 0.530 μM
human 5-HT1B Receptor, Ki: 0.549 μM
human 5-HT1D Receptor, Ki: 0.575 μM
human 5-HT1E Receptor, Ki: 1.415 μM
human 5-HT2B Receptor, Ki: 1.695 μM
Human 5-HT2A Receptor, Ki: 3.499 μM
Human 5-HT3A Receptor, Ki: 3.935 mM
     
Human 5-HT7 Receptor , Ki: 4.851 μM
  98.93%
Quetiapine hemifumarate
5-HT1A Receptor, pKi: 5.74
5-HT1A Receptor, pEC50: 4.77
5-HT2A Receptor, pKi: 7.54
5-HT2C Receptor, pKi: 5.55
            99.94%
GSK163090
5-HT1A Receptor, pKi: 9.4
5-HT1B Receptor, pKi: 8.5
5-HT1D Receptor, pKi: 9.7
5-HT2A Receptor, pKi: 6
5-HT2B Receptor, pKi: 6.3
5-HT2C Receptor, pKi: 5.8
     
Human 5-HT6 Receptor, pKi: <5.3
Human 5-HT7 Receptor , pKi: 6.8
  99.77%
UNC9994 hydrochloride
5-HT1A Receptor, Ki: 26 nM
5-HT2A Receptor, Ki: 140 nM
5-HT2B Receptor, Ki: 25 nM
5-HT2C Receptor, Ki: 512 nM
           
GR 125743
human 5-HT1B Receptor, pKi: 8.85
human 5-HT1D Receptor, pKi: 8.31
              99.78%
cis-Urocanic acid  
5-HT2A Receptor
            99.92%
PF-04995274      
5-HT4 Receptor
        99.95%
Cyamemazine  
5-HT2A Receptor, Ki: 1.5 nM
5-HT2C Receptor, Ki: 12 nM
5-HT3 Receptor, Ki: 75 nM
          ≥99.0%
8-OH-DPAT hydrobromide
5-HT1A Receptor, pIC50: 8.19
              ≥99.0%
Urapidil
5-HT1A Receptor
              99.94%
Rizatriptan benzoate
5-HT1 Receptor
              99.93%
F 13714 fumarate
5-HT1A Receptor
              98.65%
Bemesetron    
5-HT3 Receptor, IC50: 0.33 nM
          ≥99.0%
Deramciclane  
5-HT2A Receptor
5-HT2C Receptor
            98.13%
Sarizotan
5-HT1D Receptor, IC50: 500 nM (calf)
5-HT1A Receptor, IC50: 6.5 nM (rat)
5-HT1A Receptor, IC50: 0.1 nM (human)
5-HT1B Receptor, IC50: 600 nM (rat)
5-HT2A Receptor, IC50: 960 nM (rat, agonist site)
5-HT2A Receptor, IC50: 587 nM (human, antagonist site)
5-HT2C Receptor, IC50: 800 nM (pig)
5-HT2B Receptor, IC50: 108 nM (human)
5-HT3 Receptor, IC50: 3500 nM (NG 108 cells)
 
5-HT5A Receptor, IC50: 313 nM (human)
5-HT6 Receptor, IC50: 3300 nM (human)
5-HT7 Receptor, IC50: 10 nM (human)
  98.74%
(Rac)-Rotigotine hydrochloride
5-HT1A Receptor, Ki: 30 nM
5-HT2B Receptor, Ki: 27 nM
            98.66%
Eltoprazine hydrochloride
5-HT1A Receptor
5-HT1B Receptor
5-HT2C Receptor
            99.85%
Tianeptine              
serotonin
99.24%
Cyproheptadine hydrochloride sesquihydrate  
5-HT2 Receptor
            99.00%
F-15599
5-HT1A Receptor, Ki: 3.4 nM
              99.82%
Urapidil hydrochloride
5-HT1A Receptor
              ≥99.0%
Ecopipam hydrobromide              
5-HT Receptor, Ki: 80 nM
≥99.0%
Tropisetron    
5-HT3 Receptor, IC50: 70.1 nM
         
DSP-1053
5-HT1A Receptor, Ki: 5.05 nM
              99.72%
Befiradol hydrochloride
5-HT1A Receptor
              99.74%
RS 39604      
5-HT4 Receptor, pKi: 9.1
       
Ro60-0175  
5-HT2C Receptor
            99.98%
PRX-07034 hydrochloride
5-HT1A Receptor, Ki: 420 nM
5-HT1B Receptor, Ki: 260 nM
5-HT1D Receptor, Ki: 2.8 μM
5-HT2A Receptor, IC50: 2.5 μM
5-HT2B Receptor, IC50: 2.5 μM
5-HT2C Receptor, IC50: 3.7 μM
     
5-HT6 Receptor, Ki: 4-8 nM
5-HT6 Receptor, IC50: 19 nM
    98.09%
Velusetrag      
5-HT4 Receptor, pKi: 7.7
        99.64%
Iferanserin  
5-HT2A Receptor
            99.74%
Desmethyl cariprazine
5-HT1A Receptor, Ki: 2.6 nM
             
Flopropione
5-HT1A Receptor
              98.93%
BW-723C86  
5-HT2B Receptor
            99.80%
Didesmethyl cariprazine
5-HT1A Receptor
              99.79%
PU02    
5-HT3A Receptor, IC50: 0.36 μM
5-HT 3 AB, IC50: 0.73 μM
          99.29%
Brilaroxazine
5-HT1A Receptor, Ki: 1.5 nM
5-HT2A Receptor, Ki: 2.5 nM
5-HT2B Receptor, Ki: 0.19 nM
       
5-HT7 Receptor, Ki: 2.7 nM
  98.29%
Relenopride hydrochloride  
5-HT2A Receptor, Ki: 600 nM
5-HT2B Receptor, Ki: 31 nM
5-HT2B Receptor, IC50: 2.1 μM
 
5-HT4 Receptor, Ki: 4.96 nM
        99.13%
Pimethixene maleate
5-HT1A Receptor, pKi: 7.63
5-HT2A Receptor, pKi: 10.22
5-HT2B Receptor, pKi: 10.44
5-HT2C Receptor, pKi: 8.42
            99.94%
Valerenic acid        
5-HT5A Receptor, IC50: 17.2 μM
      ≥99.0%
LY 344864 racemate
5-HT1F Receptor
              98.07%
Dolasetron Mesylate hydrate    
5-HT3 Receptor
          ≥99.0%
Pardoprunox hydrochloride
5-HT1A Receptor, pEC50: 6.3
              98.24%
Revexepride      
5-HT4 Receptor
        99.84%
Lidanserin  
5-HT2A Receptor
            ≥98.0%
AVN-492          
5-HT6 Receptor, Ki: 91 pM
    99.49%
Rodatristat ethyl
5-HT1 Receptor
             
Usmarapride      
5-HT4 Receptor, EC50: 44 nM
        ≥98.0%
Peptide 401              
serotonin
BIMU 8      
5-HT4 Receptor, EC50: 18 nM
        ≥99.0%
SKF-83566 hydrobromide  
5-HT2 Receptor, Ki: 11 nM
           
Eplivanserin hemifumarate  
5-HT2A Receptor, IC50: 5.8 nM
5-HT2C Receptor, IC50: 120 nM
            98.07%
4F 4PP oxalate  
5-HT2A Receptor, Ki: 5.3 nM
5-HT2C Receptor, Ki: 620 nM
            98.08%
SB 243213 dihydrochloride
human 5-HT1A Receptor, pKi: <5.3
human 5-HT1B Receptor, pKi: 5.5
human 5-HT1D Receptor, pKi: 6.32
human 5-HT1E Receptor, pKi: <5.4
human 5-HT1F Receptor, pKi: 5.35
Human 5-HT2C Receptor, pKi: 9.37
Human 5-HT2A Receptor, pKi: 7.01
human 5-HT2B Receptor, pKi: 7.2
     
Human 5-HT6 Receptor, pKi: 6.5
Human 5-HT7 Receptor , pKi: 5.64
  ≥99.0%
Mirtazapine D3  
5-HT2 Receptor
5-HT3 Receptor
          99.49%
NPS ALX Compound 4a          
5-HT6 Receptor, IC50: 7.2 nM
5-HT6 Receptor, Ki: 0.2 nM
    ≥99.0%
Fabesetron    
5-HT3 Receptor
5-HT4 Receptor
       
Temanogrel  
5-HT2A Receptor, Ki: 4.9 nM
            98.94%
Strictosidinic acid              
5-HT Receptor
GR127935 hydrochloride
5-HT1B Receptor, pKi: 8.5
5-HT1D Receptor, pIC50: 8.5
              ≥98.0%
EMD 56551
5-HT1A Receptor
             
Felcisetrag      
huamn 5-HT4(c) Receptor, pKi: 9.4
        99.65%
5-HT1A modulator 1  
5-HT2A Receptor, IC50: 500 nM
5-HT2C Receptor, IC50: 4000 nM
           
E-3620    
5-HT3 Receptor
         
SB 243213 hydrochloride
human 5-HT1A Receptor, pKi: <5.3
human 5-HT1B Receptor, pKi: 5.5
human 5-HT1D Receptor, pKi: 6.32
human 5-HT1E Receptor, pKi: <5.4
human 5-HT1F Receptor, pKi: 5.35
Human 5-HT2C Receptor, pKi: 9.37
Human 5-HT2A Receptor, pKi: 7.01
human 5-HT2B Receptor, pKi: 7.2
     
Human 5-HT6 Receptor, pKi: 6.5
Human 5-HT7 Receptor , pKi: 5.64
 
Indophagolin          
5-HT6 Receptor, IC50: 1.0 μM
    98.05%
Hypidone hydrochloride
5-HT1A Receptor
              99.82%
OPC-14523 free base
5-HT1A Receptor, IC50: 2.3 nM
             
Repinotan
5-HT1A Receptor, Ki: 0.19 nM (In calf hippocampus)
5-HT1A Receptor, Ki: 0.25 nM (In rat and human cortex)
5-HT1A Receptor, Ki: 0.59 nM (In rat hippocampus)
         
5-HT7 Receptor, Ki: 6 nM
 
(R)-Mirtazapine    
5-HT3 Receptor
          99.79%
Frovatriptan succinate hydrate
5-HT1B Receptor, pEC50: 8.2
              99.60%
CJ033466      
5-HT4 Receptor, EC50: 9 nM
        98.29%
Almotriptan
5-HT1B Receptor
5-HT1D Receptor
             
Dehydroaripiprazole
5-HT1A Receptor, Ki: 4.2 nM
              99.42%
SB228357  
5-HT2A Receptor, pKi: 6.9
5-HT2C Receptor, pKi: 9
5-HT2B Receptor, pKi: 8
            ≥99.0%
SB-200646A  
5-HT2B Receptor, pKi: 7.5
5-HT2C Receptor, pKi: 6.9
5-HT2A Receptor, pKi: 5.2
            99.47%
Alniditan dihydrochloride
human 5-HT1B Receptor, IC50: 1.7 nM
human 5-HT1D Receptor, IC50: 1.3 nM
5-HT1B Receptor, Kd: 0.9 nM
5-HT1D Receptor, Kd: 1.2 nM
             
Tedatioxetine hydrobromide  
5-HT2A Receptor
5-HT2C Receptor
5-HT3 Receptor
          99.98%
Naluzotan
5-HT1A Receptor, IC50: 20 nM
5-HT1A Receptor, Ki: 5.1 nM
              98.05%
Velusetrag hydrochloride      
5-HT4 Receptor, pKi: 7.7
       
Facinicline hydrochloride    
5-HT3 Receptor, Ki: 1.2 nM
          99.93%
ST1936  
5-HT2B Receptor, Ki: 245 nM
     
5-HT6 Receptor, Ki: 13 nM
5-HT7 Receptor, Ki: 168 nM
  99.70%
(S)-Mirtazapine  
5-HT2 Receptor
5-HT3 Receptor
          99.76%
Ipsapirone
5-HT1A Receptor
              99.87%
cis-(Z)-Flupentixol dihydrochloride  
5-HT2A Receptor, Ki: 7 nM
           
Cerlapirdine          
5-HT6 Receptor
    98.72%
Tetrahydro-β-carboline              
serotonin, Ki: 6.1 μM
Granisetron    
5-HT3 Receptor, IC50: 17 μM
         
Risperidone hydrochloride  
5-HT2 Receptor, Ki: 4.8 nM
           
Alosetron    
5-HT3 Receptor
         
Mosapride      
5-HT4 Receptor
       
Agomelatine hydrochloride  
5-HT2C Receptor, pKi: 6.4 (native porcine)
5-HT2C Receptor, pKi: 6.2 (human)
            99.55%
Isocorynoxeine  
5-HT2A Receptor, IC50: 72.4 μM
            99.97%
Eltoprazine
5-HT1A Receptor
5-HT1B Receptor
5-HT2C Receptor
           
Pimethixene
5-HT1A Receptor, pKi: 7.63
5-HT2A Receptor, pKi: 10.22
5-HT2B Receptor, pKi: 10.44
5-HT2C Receptor, pKi: 8.42
           
Ziprasidone hydrochloride
Rat 5-HT1A Receptor, Ki: 3.4 nM
Rat 5-HT2A, Ki: 0.42 nM
           
Palonosetron    
5-HT3 Receptor
         
5-HT6/7 antagonist 1  
5-HT2A Receptor
     
5-HT6 Receptor
5-HT7 Receptor
 
Lintopride    
5-HT3 Receptor
5-HT4 Receptor
       
Naratriptan
5-HT1 Receptor
             
Lesopitron dihydrochloride
5-HT1A Receptor, IC50: 125 nM (in rat hippocampal membranes)
             
(±)-Fabesetron hydrochloride    
5-HT3 Receptor
5-HT4 Receptor
       
WAY-100635
5-HT1A Receptor, pIC50: 8.87
5-HT1A Receptor, pA2: 9.71
             
SB-269970            
Human 5-HT7 Receptor , pKi: 8.3
 
AM9405    
5-HT3 Receptor, IC50: 0.076 nM
         
Rodatristat              
serotonin
Blonanserin dihydrochloride  
5-HT2A Receptor, Ki: 0.812 nM
5-HT2C Receptor, Ki: 26.4 nM
     
5-HT6 Receptor, Ki: 11.7 nM
   
UCSF648        
5-HT5A Receptor
     
SB 271046          
5-HT6 Receptor, pKi: 8.92-9.09
   
Mosapride citrate dihydrate      
5-HT4 Receptor
       
Tegaserod      
5-HT4 Receptor
       
SEP-363856
5-HT1A Receptor, EC50: 2.3 μM
5-HT1B Receptor, EC50: 15.6 μM
5-HT1D Receptor, EC50: 0.262 μM
5-HT2A Receptor, EC50: >10 μM
5-HT2C Receptor, EC50: 30 μM
       
5-HT7 Receptor, EC50: 6.7 μM
 
Usmarapride free base      
5-HT4 Receptor, EC50: 44 nM
        99.91%
RU 24969 hemisuccinate
5-HT1A Receptor, Ki: 2.5 nM
5-HT1B Receptor, Ki: 0.38 nM
             
Cariprazine-d6
5-HT1A Receptor, Ki: 2.6 nM
             
MAO-A/5-HT2AR-IN-1  
5-HT2A Receptor, IC50: 0.014 μM
           
Befiradol
5-HT1A Receptor
             
LY320135  
5-HT2 Receptor, Ki: 6.4 μM
           
Aripiprazole monohydrate
5-HT1A Receptor
5-HT2A Receptor
5-HT2B Receptor
5-HT2C Receptor
           
U92016A hydrochloride
5-HT1A Receptor, Ki: 0.2 nM
             
WAY 163909  
5-HT2C Receptor, Ki: 10.5±1.1 nM
           
PRX933 hydrochloride  
5-HT2C Receptor
           
Sumatriptan
5-HT1A Receptor, Ki: 100 nM
5-HT1B Receptor, Ki: 27 nM
5-HT1D Receptor, Ki: 17 nM
             
Blonanserin-d5  
5-HT2 Receptor
           
Viloxazine  
Human 5-HT2C Receptor, EC50: 32 μM
human 5-HT2B Receptor, IC50: 27 μM
           
WAY-100135 dihydrochloride
5-HT1A Receptor, IC50: 34 nM
             
5-HT6/5-HT2A receptor ligand-2  
5-HT2A Receptor, Ki: 32 nM
     
5-HT6 Receptor, Ki: 25 nM
   
Eletriptan
5-HT1B Receptor, pKi: 8.0
5-HT1D Receptor, pKi: 8.9
             
PNU-142633
5-HT1D Receptor, Ki: 6 nM
              ≥98.0%
SB-215505  
5-HT2B Receptor, pKi: 8.3
5-HT2A Receptor, pKi: 6.77
5-HT2C Receptor, pKi: 7.66
           
PNU-96415E  
5-HT2A Receptor
           
5-HT2B antagonist-1  
5-HT2B Receptor, IC50: 33.4 nM
            99.86%
PNU-282987 free base    
5-HT3 Receptor
         
3-Hydroxy agomelatine  
5-HT2C Receptor, IC50: 3.2 μM
5-HT2C Receptor, Ki: 1.8 μM
           
5-HT6/5-HT2A receptor ligand-1  
5-HT2A Receptor, IC50: 11 nM
     
5-HT6 Receptor, Ki: 2 nM
   
Isopteropodine  
5-HT2 Receptor
            98.66%
SB 258719 hydrochloride            
5-HT7 Receptor, pKi: 7.5
 
Brexpiprazole hydrochloride
5-HT1A Receptor, Ki: 0.12 nM
5-HT2A Receptor, Ki: 0.47 nM
           
Masupirdine mesylate          
5-HT6 Receptor, Ki: 2.04 nM
   
Brexpiprazole S-oxide D8
5-HT1A Receptor, Ki: 0.12 nM
5-HT2A Receptor, Ki: 0.47 nM
           
2-Methyl-5-HT hydrochloride    
5-HT3 Receptor
         
5-HT6/5-HT2AR antagonist-1  
5-HT2A Receptor, Ki: 39 nM
     
5-HT6 Receptor, Ki: 11 nM
   
BRL-15572 hydrochloride
5-HT1D Receptor
             
SB-221284  
5-HT2A Receptor, pKi: 6.4
5-HT2B Receptor, pKi: 7.9
5-HT2C Receptor, pKi: 8.6
           
BMY 7378
5-HT1A Receptor
             
Isamoltane hemifumarate
5-HT1B Receptor, IC50: 39 nM
             
Tandospirone hydrochloride
5-HT1A Receptor, Ki: 27 nM
             
MK-212
5-HT1C Receptor
5-HT2 Receptor
           
Blonanserin D8  
5-HT2 Receptor
           
5-HT7 receptor ligand 1            
5-HT7 Receptor, Ki: 8 nM
 
SCH-23390 maleate  
5-HT2C Receptor, Ki: 9.3 nM
           
7-Desmethyl-3-hydroxyagomelatine  
5-HT2C Receptor
           
WAY-181187 oxalate          
5-HT6 Receptor, Ki: 2.2 nM
5-HT6 Receptor, EC50: 6.6 nM
   
MK-212 monohydrochloride
5-HT1C Receptor
5-HT2 Receptor
           
Flibanserin hydrochloride
5-HT1A Receptor, Ki: 1 nM
5-HT2A Receptor, Ki: 49 nM
           
DSP-1053 benzenesulfonate
5-HT1A Receptor, Ki: 5.05 nM
             
Perospirone hydrochloride
5-HT1A Receptor, Ki: 2.9 nM
5-HT1 Receptor, Ki: 18 nM
5-HT2A Receptor, Ki: 0.6 nM
           
Ecopipam              
5-HT Receptor, Ki: 80 nM
RS 67333 hydrochloride      
5-HT4 Receptor, pKi: 8.7
       
Asimilobine              
serotonergic receptor
LP 12 hydrochloride
5-HT1A Receptor, IC50: 60.9 nM
5-HT2A Receptor, IC50: 1464 nM
       
5-HT7 Receptor, IC50: 0.13 nM
 
Trimipramine
5-HT1C Receptor, pKi: 6.39
5-HT1A Receptor, pKi: 4.66
5-HT2 Receptor, pKi: 8.10
           
Bifeprunox
5-HT1A Receptor, pKi: 7.19 (cortex)
5-HT1A Receptor, pEC50: 6.37 (hippocampus)
             
Eplivanserin  
5-HT2A Receptor, IC50: 5.8 nM (in rat cortical membrane)
5-HT2A Receptor, Ki: 1.14 nM
5-HT2C Receptor, IC50: 120 nM
           
EMD386088          
5-HT6 Receptor
   
Naronapride      
5-HT4 Receptor
       
Ro 04-6790          
Rat 5-HT6 Receptor, pKi: 7.26
Human 5-HT6 Receptor, pKi: 7.35
   
3-Hydroxy agomelatine D3  
5-HT2C Receptor, IC50: 3.2 μM
5-HT2C Receptor, Ki: 1.8 μM
           
ST1936 oxalate  
5-HT2B Receptor, Ki: 245 nM
     
5-HT6 Receptor, Ki: 13 nM
Human 5-HT7 Receptor , Ki: 168 nM
 
(R)-Mirtazapine D3    
5-HT3 Receptor
         
Ecopipam hydrochloride              
5-HT Receptor, Ki: 80 nM
SB 258741 hydrochloride            
5-HT7 Receptor
 
Eplivanserin (mixture)  
5-HT2A Receptor
            99.77%
Opiranserin hydrochloride  
5-HT2A Receptor, IC50: 1.3 μM
            99.44%
Org-12962  
5-HT2C Receptor, pEC50: 7.01
5-HT2A Receptor, pEC50: 6.38
5-HT2B Receptor, pEC50: 6.28
            ≥98.0%
5-HT1A antagonist 1
5-HT1A Receptor, Ki: 35 nM
5-HT2A Receptor, Ki: 530 nM
       
5-HT7 Receptor, Ki: 462 nM
 
Ziprasidone mesylate trihydrate
Rat 5-HT1A Receptor, Ki: 3.4 nM
Rat 5-HT2 Receptor, Ki: 0.42 nM
           
AR-A 2
5-HT1A Receptor, Ki: 3070 nM
5-HT1B/D Receptor, Ki: 20 nM
5-HT2A Receptor, Ki: 339 nM
           
Sarpogrelate  
5-HT2 Receptor
           
A-582941 dihydrochloride    
5-HT3 Receptor, Ki: 150 nM
         
LY-272015 hydrochloride  
5-HT2B Receptor
           
Asenapine citrate
5-HT1A Receptor, pKi: 8.6
5-HT1B Receptor, pKi: 8.4
5-HT2A Receptor, pKi: 10.2
5-HT2C Receptor, pKi: 10.5
5-HT2B Receptor, pKi: 9.8
   
5-HT5 Receptor, pKi: 8.8
5-HT6 Receptor, pKi: 9.6
5-HT7 Receptor, pKi: 9.9
 
Mesembrine              
serotonin, Ki: 1.4 nM
(Rac)-WAY-161503  
5-HT2C Receptor, Ki: 4 nM
5-HT2C Receptor, EC50: 12 nM
            ≥99.0%
CART(62-76)(human,rat)              
serotonin
DR4485 hydrochloride            
5-HT7 Receptor, pKi: 8.14
 
Cisapride monohydrate      
5-HT4 Receptor, EC50: 0.14 μM
       
EMDT oxalate          
5-HT6 Receptor
   
LY266097 hydrochloride  
5-HT2B Receptor, pKi: 9.8
5-HT2A Receptor, pKi: 7.7
5-HT2C Receptor, pKi: 7.6
           
Urapidil D6
5-HT1A Receptor
             
TIK-301  
5-HT2C Receptor
5-HT2B Receptor
           
Loxapine hydrochloride  
human 5-HT2
           
MM 77 dihydrochloride
5-HT1A Receptor
             
AP521
5-HT1A Receptor, IC50: 94 nM (in human)
5-HT1A Receptor, IC50: 135 nM (in rat)
5-HT1B Receptor, IC50: 254 nM (in rat)
5-HT1B Receptor, IC50: 5530 nM (in human)
5-HT1D Receptor, IC50: 418 nM (in human)
     
5-HT5A Receptor, IC50: 422 nM (in human)
 
5-HT7 Receptor, IC50: 198 nM (in rat)
  98.96%
GR-46611
5-HT1D Receptor
              99.82%
Norfluoxetine hydrochloride              
5-HT Receptor
Ro60-0175 fumarate  
5-HT2C Receptor
           
Opiranserin  
5-HT2A Receptor, IC50: 1.3 μM
           
(S)-Amisulpride            
5-HT7 Receptor, Ki: 900 nM
  99.75%
BGC20-761  
Human 5-HT2A Receptor, Ki: 69 nM
     
Human 5-HT6 Receptor, Ki: 20 nM
   
5-HT7 agonist 1            
5-HT7 Receptor
 
PF-4479745
5-HT1A Receptor, IC50: 500 nM
5-HT2C Receptor, EC50: 10 nM
5-HT2C Receptor, Ki: 15 nM
5-HT2A Receptor, IC50: 360 nM
5-HT2B Receptor, IC50: 67 nM
     
5-HT6 Receptor, IC50: 280 nM
   
RS-127445  
5-HT2B Receptor, pKi: 9.5 nM
           
Syk Inhibitor II dihydrochloride dihydrate              
serotonin, IC50: 460 nM
Ziprasidone mesylate
Rat 5-HT1A Receptor, Ki: 3.4 nM
Rat 5-HT2 Receptor, Ki: 0.42 nM
           
NEO 376
5-HT1 Receptor
              99.23%
Nemonapride
5-HT1A Receptor, IC50: 34 nM
             
CART(62-76)(human,rat) TFA              
serotonin
VUF10166    
5-HT3A Receptor, Ki: 0.04 nM
5-HT 3 AB, Ki: 22 nM
         
Aripiprazole-d8  
5-HT2A Receptor
5-HT2C Receptor
           
Perphenazine dihydrochloride
5-HT1A Receptor, Ki: 421 nM
5-HT2A Receptor, Ki: 5.6 nM
5-HT2C Receptor, Ki: 132 nM
     
5-HT6 Receptor, Ki: 17 nM
5-HT7 Receptor, Ki: 23 nM
 
YM348  
5-HT2A Receptor, Ki: 13 nM
5-HT2B Receptor, Ki: 2.5 nM
5-HT2C Receptor, Ki: 0.89 nM
5-HT2A Receptor, EC50: 93 nM
5-HT2B Receptor, EC50: 3.2 nM
5-HT2C Receptor, EC50: 1 nM
           
LY 344864 hydrochloride
human 5-HT1F Receptor, Ki: 0.006 μM
human 5-HT1A Receptor, Ki: 0.530 μM
human 5-HT1B Receptor, Ki: 0.549 μM
human 5-HT1D Receptor, Ki: 0.575 μM
human 5-HT1E Receptor, Ki: 1.415 μM
human 5-HT2B Receptor, Ki: 1.695 μM
Human 5-HT2C Receptor, Ki: 3.499 μM
Human 5-HT3A Receptor, Ki: 3.935 μM
     
Human 5-HT7 Receptor , Ki: 4.851 μM
 
NAS-181 dimesylate
Rat 5-HT1B Receptor, IC50: 47 nM
              98.44%
LE 300  
Rat 5-HT2A, pA2: 8.32
           
BMY-14802 hydrochloride
5-HT1A Receptor
             
5-HT3 antagonist 5    
5-HT3 Receptor
          99.75%
Sumatriptan hydrochloride
5-HT1D Receptor, Ki: 17 nM
5-HT1B Receptor, Ki: 27 nM
5-HT1A Receptor, Ki: 100 nM
             
SGS518 oxalate          
5-HT6 Receptor
   
Org-12962 hydrochloride  
5-HT2C Receptor, pEC50: 7.01
5-HT2A Receptor, pEC50: 6.38
5-HT2B Receptor, pEC50: 6.28
           
(R)-Praziquantel-d11  
5-HT2B Receptor
           
UNC9994
5-HT1F Receptor, Ki: 26 nM
5-HT2A Receptor, Ki: 140 nM
5-HT2B Receptor, Ki: 25 nM
5-HT2C Receptor, Ki: 512 nM
           
ML 10302 hydrochloride    
5-HT3 Receptor, Ki: 782 nM
5-HT4 Receptor, EC50: 4 nM
5-HT4 Receptor, Ki: 1.07 nM
       
NPS ALX Compound 4a dihydrochloride          
5-HT6 Receptor, IC50: 7.2 nM
5-HT6 Receptor, Ki: 0.2 nM
   
Frovatriptan succinate
5-HT1B Receptor, pEC50: 8.2
             
SB-200646  
5-HT2B Receptor, pKi: 7.5
5-HT2C Receptor, pKi: 6.9
5-HT2A Receptor, pKi: 5.2
           
5-HT4 antagonist 1      
5-HT4 Receptor, pKi: 9.6
        98.67%
5-HT6R/MAO-B modulator 1          
5-HT6 Receptor
   
Brexpiprazole S-oxide
5-HT1A Receptor, Ki: 0.12 nM
5-HT2A Receptor, Ki: 0.47 nM
           
Masupirdine free base          
5-HT6 Receptor, Ki: 2.04 nM
   
Renzapride      
5-HT4 Receptor, Ki: 115 nM
       
2-Methyl-5-HT maleate    
5-HT3 Receptor
         
F 13714
5-HT1A Receptor, pKi: 10.23
5-HT1B Receptor, pIC50: 5.12
             
Risperidone mesylate  
5-HT2A Receptor, Ki: 4.8 nM
           
Iloperidone hydrochloride
Rat 5-HT1A Receptor, Ki: 168 nM
Rat 5-HT2 Receptor, Ki: 3.1 nM
Human 5-HT2A Receptor, Ki: 5.6 nM
Human 5-HT2C Receptor, Ki: 42.8 nM
     
Rat 5-HT6 Receptor, Ki: 42.7 nM
Rat 5-HT7 Receptor, Ki: 21.6 nM
 
Agomelatine (L(+)-Tartaric acid)  
5-HT2C Receptor, pKi: 6.4 (native porcine)
5-HT2C Receptor, pKi: 6.2 (human)
            99.82%
Alosetron ((Z)-2-butenedioate)    
5-HT3 Receptor
         
Pardoprunox
5-HT1A Receptor, pEC50: 6.3
             
Dolasetron Mesylate    
5-HT3 Receptor
         
Alosetron (Hydrochloride(1:X))    
5-HT3 Receptor
         
Idalopirdine          
5-HT6 Receptor, Ki: 0.83 nM
   
Pizotifen malate  
5-HT2A Receptor
           
Piboserod hydrochloride      
5-HT4 Receptor
       
Nexopamil racemate  
5-HT2 Receptor
           
Abaperidone  
5-HT2A Receptor, IC50: 6.2 nM
           
Irindalone  
5-HT2 Receptor
           
Pancopride    
5-HT3 Receptor
         
Sulamserod      
5-HT4 Receptor
       
Alniditan
human 5-HT1B Receptor, IC50: 1.7 nM (in HEK 293 cell)
human 5-HT1D Receptor, IC50: 1.3 nM (in HEK 293 cell)
5-HT1B Receptor, Kd: 0.9 nM
5-HT1D Receptor, Kd: 1.2 nM
             
RG-12915    
5-HT3 Receptor, IC50: 0.16 nM
         
MHP 133      
5-HT4 Receptor
       
Wf-516
5-HT1A Receptor, Ki: 5 nM
5-HT2A Receptor, Ki: 40 nM
           
T 82    
5-HT3 Receptor
         
Ondansetron hydrochloride    
5-HT3 Receptor
         
CP-809101  
5-HT2C Receptor, pEC50: 9.96
5-HT2B Receptor, pEC50: 7.19
5-HT2A Receptor, pEC50: 6.81
           
CGS 12066 dimaleate
5-HT1B Receptor, IC50: 51 nM
             
Zatosetron maleate    
5-HT3 Receptor
         
(4E)-SUN9221  
5-HT2 Receptor
           
5-HT3 antagonist 1    
5-HT3 Receptor
         
5-HT3 antagonist 3    
5-HT3 Receptor, Ki: 0.25 nM
         
5-HT3-In-1    
5-HT3 Receptor
         
5-HT2 antagonist 1  
5-HT2 Receptor
           
5-HT3 antagonist 2    
5-HT3 Receptor
         
5-HT2A antagonist 1  
5-HT2A Receptor
           
5HT6-ligand-1          
5-HT6 Receptor, Ki: 1.43 nM