2. Cell Cycle/DNA Damage Apoptosis
  3. Topoisomerase Apoptosis
  4. Topoisomerase II inhibitor 9

Topoisomerase II inhibitor 9 (Compound 19b) is a Topo II inhibitor with an IC50 of 0.97 μM. Topoisomerase II inhibitor 9 is also a classical DNA-intercalator with an IC50 of 43.51 μM. Topoisomerase II inhibitor 9 arrests the cell cycle at the G2/M phase and induces apoptosis in Hep G‐2 cells.

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Topoisomerase II inhibitor 9

Topoisomerase II inhibitor 9 構造式

CAS 番号 : 2413901-61-6

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Topoisomerase II inhibitor 9 関連抗体

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Topoisomerase Topo I Topo II DNA gyrase

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製品説明

Topoisomerase II inhibitor 9 (Compound 19b) is a Topo II inhibitor with an IC50 of 0.97 μM. Topoisomerase II inhibitor 9 is also a classical DNA-intercalator with an IC50 of 43.51 μM. Topoisomerase II inhibitor 9 arrests the cell cycle at the G2/M phase and induces apoptosis in Hep G‐2 cells[1].

IC50 & Target

Topoisomerase II

0.97 μM (IC50)

体外実験

Topoisomerase II inhibitor 9 (Compound 19b) shows antiproliferative activity with IC50 values of 0.50 ± 0.1, 0.75 ± 0.1 and 2.91 ± 0.1 μM against Hep G‐2, Hep‐2 and Caco‐2 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Topoisomerase II inhibitor 9 関連抗体
分子量

491.55

分子式

C22H17N7O3S2
CAS 番号
SMILES

O=C(NC1=CC=C(S(=O)(NC2=NC=CC=C2)=O)C=C1)CSC3=NC4=C(N5C3=NN=C5)C=CC=C4
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
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参考文献
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Topoisomerase II inhibitor 9 Related Classifications

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Keywords:

Topoisomerase II inhibitor 92413901-61-6Topoisomerase II inhibitor9Topoisomerase II inhibitor-9TopoisomeraseApoptosisHep G‐2Hep‐2Caco‐2anticancerBcl‐2BaxInhibitorinhibitorinhibit

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製品名:
Topoisomerase II inhibitor 9
製品番号:
HY-146189
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