AChE-IN-20
AChE-IN-20 (compound M26) is a potent AChE inhibitor with IC50 value of 397.32 nM and with Ki value of 335.76 nM. AChE-IN-20 shows inhibition potency against hCA I , hCA II and α-GLY with IC50 values of 84.14, 69.24 and 52.08 nM and with Ki values of 97.86, 76.23 and 57.93 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2428389-65-3
- Formula: C22H20N8O6S2
- Molecular Weight:556.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AChE 397.32 nM (IC50) |
AChE 335.76 nM (Ki) |
Chemical Information
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CAS No. 2428389-65-3
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Molecular Weight 556.57
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Formula C22H20N8O6S2
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SMILES
O=C(C1=CC=C(NC2=NC(NC3=CC=C(S(=O)(N)=O)C=C3)=NC(NC4=CC=C(S(=O)(N)=O)C=C4)=N2)C=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lolak N, et al. Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs. Bioorg Chem. 2020 Jul;100:103897. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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