Telmisartan (Standard)
Telmisartan (Standard) is the analytical standard of Telmisartan. This product is intended for research and analytical applications. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98%
- No. CAS: 144701-48-4
- Fòrmula: C33H30N4O2
- Peso molecular:514.62
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-13955
TelmisartanAngiotensin II Type 1 Receptor -
HY-B0205
CandesartanAngiotensin II AT1-Receptor Blocker -
HY-17512A
Losartan potassiumAT1 Antagonist -
HY-B0368
CaptoprilACE Inhibitor -
HY-18204
ValsartanAngiotensin II Receptor Antagonist -
HY-B0202
IrbesartanAT1 Receptor Blocker -
HY-17512AR
Losartan potassium (Standard)AT1 Antagonist -
HY-14914
AzilsartanAT1 Antagonist -
HY-17504
Rosuvastatin CalciumHMGCR Inhibitor -
HY-17512
LosartanAngiotensin II Receptor Antagonist -
HY-13948A
Angiotensin II human acetateVasoconstrictor -
HY-B0205R
Candesartan (Standard)Angiotensin II AT1-Receptor Blocker
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 144701-48-4
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Peso molecular 514.62
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Fòrmula C33H30N4O2
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SMILES
O=C(C1=CC=CC=C1C2=CC=C(CN3C4=CC(C5=NC6=CC=CC=C6N5C)=CC(C)=C4N=C3CCC)C=C2)O
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Synonyms
BIBR 277 (Standard)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Maillard MP, et al. In vitro and in vivo characterization of the activity of telmisartan: an insurmountable angiotensin II receptor antagonist. J Pharmacol Exp Ther. 2002 Sep;302(3):1089-95. [Content Brief]
[2]. Xuan H, et al. Inhibition or deletion of angiotensin II type 1 receptor suppresses elastase-induced experimental abdominal aortic aneurysms. J Vasc Surg. 2017 Apr 20. pii: S0741-5214(17)30100-3. [Content Brief]
[3]. Torika N, et al. Intranasal telmisartan ameliorates brain pathology in five familial Alzheimer's disease mice. Brain Behav Immun. 2017 Apr 3. [Content Brief]
[4]. Aswar U, et al. Telmisartan attenuates diabetes induced depression in rats. Pharmacol Rep. 2017 Apr;69(2):358-364. [Content Brief]
[5]. Fujihara S, et al. The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKα/mTOR pathway in vitro and in vivo. Oncotarget. 2017 Jan 31;8(5):8536-8549. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Telmisartan (Standard) Related Classifications
HY-13955R Related Classifications
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