Cu(II) protoporphyrin IX
Based on 1 Customer Validation
Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair.
For research use only. We do not sell to patients.
- Purity: 95.60%
- CAS No.: 14494-37-2
- Formula: C34H32CuN4O4
- Molecular Weight:624.19
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 14494-37-2
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Appearance Solid
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Molecular Weight 624.19
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Formula C34H32CuN4O4
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Color Brown to reddish brown
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SMILES
[O-]C(CCC(C1=CC(C(CCC([O-])=O)=C2C)=[N](C2=C3)[Cu+2]4([N-]5C3=C6C)[N-]1C7=CC(C(C=C)=C8C)=[N]4C8=CC5=C6C=C)=C7C)=O.[H+].[H+]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (275 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
[1]. Jozkowicz A, et al. Heme oxygenase-1 in tumors: is it a false friend?. Antioxid Redox Signal. 2007;9(12):2099-2117. [Content Brief]
[2]. Abraham NG, et al. Heme oxygenase and the cardiovascular-renal system. Free Radic Biol Med. 2005;39(1):1-25. [Content Brief]
[3]. Kim DH, et al. Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther. 2008;325(3):833-840. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)