Dermatan sulphate sodium

Cat. No.: HY-N8278: FAQs
Data Sheet SDS COA Handling Instructions

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Dermatan sulphate sodium is a glycosaminoglycan and thrombin inactivator with antithrombotic activity. Dermatan sulphate sodium selectively catalyzes the inactivation of thrombin by heparin cofactor II and does not interact with antithrombin III. Dermatan sulphate sodium is highly bioavailable and also reduces Bleomycin (HY-108345)-induced pulmonary fibrosis damage.

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Dermatan sulphate sodium Chemical Structure

CAS No. : 54328-33-5

Size	Price	Stock	Quantity
5 mg	USD 135	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description	Dermatan sulphate sodium is a glycosaminoglycan and thrombin inactivator with antithrombotic activity. Dermatan sulphate sodium selectively catalyzes the inactivation of thrombin by heparin cofactor II and does not interact with antithrombin III. Dermatan sulphate sodium is highly bioavailable and also reduces Bleomycin (HY-108345)-induced pulmonary fibrosis damage^[1]^[2].
CAS No.	54328-33-5
Appearance	Solid
Color	White to off-white
SMILES	N/A
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility	In Vitro: H₂O : 100 mg/mL (Need ultrasonic) DMSO : < 1 mg/mL (insoluble or slightly soluble) Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details. The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE). Tel: 609-228-6898 E-mail: [email protected] Technical Support: [email protected]
Purity & Documentation	Select Batch: Data Sheet (272 KB) SDS (251 KB) COA (255 KB) Handling Instructions (2659 KB)
References	[1]. Nenci GG. Dermatan sulphate as an antithrombotic drug. Pathophysiol Haemost Thromb. 2002 Sep-Dec;32(5-6):303-7. [Content Brief] [2]. Xu J, et al. Effect of dermatan sulphate on a C57-mouse model of pulmonary fibrosis. J Int Med Res. 2019 Jun;47(6):2655-2665. [Content Brief]