54328-33-5
54328-33-5
Chemical Structure
Biological Activity: Dermatan sulphate sodium is an oral active glycosaminoglycan and thrombin inactivator with antithrombotic activity. It selectively catalyzes the heparin cofactor II-mediated inactivation of thrombin without interacting with antithrombin III. Dermatan sulphate sodium promotes stem cell differentiation, exhibits high bioavailability, and alleviates pulmonary fibrosis injury induced by Bleomycin (HY-108345). Dermatan sulphate sodium can be used in research related to cardiovascular diseases, inflammation, and stem cell differentiation[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dermatan sulphate sodium | 95.4% | Dermatan sulphate sodium is an oral active glycosaminoglycan and thrombin inactivator with antithrombotic activity. It selectively catalyzes the heparin cofactor II-mediated inactivation of thrombin without interacting with antithrombin III. Dermatan sulphate sodium promotes stem cell differentiation, exhibits high bioavailability, and alleviates pulmonary fibrosis injury induced by Bleomycin (HY-108345). Dermatan sulphate sodium can be used in research related to cardiovascular diseases, inflammation, and stem cell differentiation. | ||||||||||||||||||||
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References
- [1]. Nenci GG. Dermatan sulphate as an antithrombotic drug. Pathophysiol Haemost Thromb. 2002 Sep-Dec;32(5-6):303-7. [Content Brief]
- [2]. Xu J, et al. Effect of dermatan sulphate on a C57-mouse model of pulmonary fibrosis. J Int Med Res. 2019 Jun;47(6):2655-2665. [Content Brief]
- [3]. Ogura C, et al. Dermatan sulphate promotes neuronal differentiation in mouse and human stem cells. J Biochem. 2021 Feb 6;169(1):55-64. [Content Brief]
Keywords
