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Cat. No.: HY-156469

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NLRP3-IN-22

NLRP3-IN-22 (Compound II-4) is a NLRP3 inhibitor (inhibition rate: 67% at 10 μM)

For research use only. We do not sell to patients.

CAS No.: 1193329-98-4
Formula: C₁₉H₁₂F₃NO₄S
Molecular Weight:407.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

NLRP3-IN-22 Chemical Structure

CAS No.: 1193329-98-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

NLRP3-IN-22 (Compound II-4) is a NLRP3 inhibitor (inhibition rate: 67% at 10 μM)^[1]

All NOD-like Receptor (NLR) Isoforms :

Chemical Information

CAS No. 1193329-98-4
Molecular Weight 407.36
Formula C₁₉H₁₂F₃NO₄S
SMILES

O=C(C1=CC=C(/C=C2SC(N(CC3=CC=CC(C(F)(F)F)=C3)C\2=O)=O)C=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhou Rongbin, et al. Thiazolinone heterocyclic compound and preparation method, pharmaceutical composition, and application thereof. Patent. WO2019001416

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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NLRP3-IN-22

All NOD-like Receptor (NLR) Isoforms