1. Protein Tyrosine Kinase/RTK
  2. Src
  3. 1-Naphthyl PP1

1-Naphthyl PP1 (Synonyms: 1-NA-PP 1)

Cat. No.: HY-13941 Purity: 98.77%
Handling Instructions

1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively.

For research use only. We do not sell to patients.

1-Naphthyl PP1 Chemical Structure

1-Naphthyl PP1 Chemical Structure

CAS No. : 221243-82-9

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 99 In-stock
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 158 In-stock
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50 mg USD 637 In-stock
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100 mg USD 1080 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively[1].

Molecular Weight

317.39

Formula

C₁₉H₁₉N₅

CAS No.

221243-82-9

SMILES

CC(N1N=C(C2=C3C=CC=CC3=CC=C2)C4=C(N)N=CN=C41)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (39.38 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1507 mL 15.7535 mL 31.5070 mL
5 mM 0.6301 mL 3.1507 mL 6.3014 mL
10 mM 0.3151 mL 1.5753 mL 3.1507 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 1.25 mg/mL (3.94 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 1.25 mg/mL (3.94 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 98.77%

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

1-Naphthyl PP11-NA-PP 1SrcInhibitorinhibitorinhibit

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Product Name:
1-Naphthyl PP1
Cat. No.:
HY-13941
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