Src Inhibitors

Lck

Fyn

Blk

Fgr

Hck

Lyn

Yes

SRC-3

Src Inhibitors, Degraders & Ligands

Product Name	Lck	Fyn	Blk	Fgr	Hck	Lyn	Yes	SRC-3	Purity
Papaveroline hydrochloride		Fyn							99.04%
Lck-IN-5	Lck								98.09%
GLPG3312	Lck, IC₅₀: 385 nM	Fyn, IC₅₀: 447 nM	Blk, IC₅₀: 730 nM		Hck, IC₅₀: 2511 nM	Lyn, IC₅₀: 272 nM	Yes, IC₅₀: 598 nM		98.63%
Velzatinib	Lck, IC₅₀: 141 nM								99.40%
PRT062607 Hydrochloride	Lck, IC₅₀: 249 nM (^[2])								98.07%
AZM475271	Lck, IC₅₀: 0.03 μM								99.89%
SB 220025	p56-Lck, IC₅₀: 3.5 μM								99.90%
SB1-G-187						Lyn			98.70%
PRT062607 acetate	Lck, IC₅₀: 249 nM (^[2])								99.83%
MRT-10350					Hck				99.10%
Papaveroline		Fyn
RK-20448	Lck, IC₅₀: 0.24 μM	Fyn, IC₅₀: 2.03 μM	Blk, IC₅₀: 0.37 μM						99.38%
DFCI-002-06					Hck, DC₅₀: 1.3 nM
BMS-279700	p56-Lck
Lck-IN-6	Lck, IC₅₀: 3 nM
LCK degrader-3	Lck
LCK degrader-2	Lck
ARN25699		Fyn-α
Hck-IN-3					Hck
LCK ligand-1	Lck
MRT-7612	Lck				Hck	Lyn
Fyn-IN-1		Fyn, IC₅₀: 0.044 μM
SJ11646	Lck, DC₅₀: 0.00838 pM
Lck-IN-2	Lck, IC₅₀: 10.6 nM
BTK-IN-45	Lck
Antifibrotic agent 1	Lck	Fyn			Hck	Lyn	Yes
BY13								SRC-3, DC₅₀: 0.031 μM
N-Deshydroxyethyl Dasatinib-C3-NH2	Lck
Aminogenistein	p56-Lck, IC₅₀: 1.2 μM
BMS-243117	Lck, IC₅₀: 4 nM	Fyn, IC₅₀: 32 nM	Blk, IC₅₀: 84 nM
SIK1-IN-1	Lck, IC₅₀: 3.7 nM			Fgr, IC₅₀: <3 nM	Hck, IC₅₀: <3 nM	Lyn, IC₅₀: <1.5 nM	Yes, IC₅₀: <3 nM

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