Src Inhibitors

Lck

Fyn

Blk

Fgr

Hck

Lyn

Yes

Csk

SRC-3

Src Inhibitors, Degraders & Ligands

Product Name	Lck	Fyn	Blk	Fgr	Hck	Lyn	Yes	Csk	SRC-3	Purity
Papaveroline hydrochloride		Fyn								99.04%
Lck-IN-5	Lck									98.09%
DFCI-002-06					Hck, DC₅₀: 1.3 nM
GLPG3312	Lck, IC₅₀: 385 nM	Fyn, IC₅₀: 447 nM	Blk, IC₅₀: 730 nM		Hck, IC₅₀: 2511 nM	Lyn, IC₅₀: 272 nM	Yes, IC₅₀: 598 nM			98.63%
Velzatinib	Lck, IC₅₀: 141 nM									99.40%
PRT062607 Hydrochloride	Lck, IC₅₀: 249 nM (^[2])									98.07%
Dasatinib metabolite M6								Csk		99.39%
AZM475271	Lck, IC₅₀: 0.03 μM									99.89%
DB-3-291								Csk		99.08%
SB 220025	p56-Lck, IC₅₀: 3.5 μM									99.90%
SB1-G-187						Lyn				98.70%
PRT062607 acetate	Lck, IC₅₀: 249 nM (^[2])									99.83%
MRT-10350					Hck					99.10%
DB-0646							Yes			98.0%
Papaveroline		Fyn
RK-20448	Lck, IC₅₀: 0.24 μM	Fyn, IC₅₀: 2.03 μM	Blk, IC₅₀: 0.37 μM							99.38%
BMS-279700	p56-Lck
Lck-IN-6	Lck, IC₅₀: 3 nM
LCK degrader-3	Lck
LCK degrader-2	Lck
ARN25699		Fyn-α
AP-24567						Lyn	Yes
Hck-IN-3					Hck
LCK ligand-1	Lck
MRT-7612	Lck				Hck	Lyn
Fyn-IN-1		Fyn, IC₅₀: 0.044 μM
SJ11646	Lck, DC₅₀: 0.00838 pM
Lck-IN-2	Lck, IC₅₀: 10.6 nM
BTK-IN-45	Lck
Antifibrotic agent 1	Lck	Fyn			Hck	Lyn	Yes
BY13									SRC-3, DC₅₀: 0.031 μM
Multi kinase ligand 4							Yes
N-Deshydroxyethyl Dasatinib-C3-NH2	Lck
WH-4-023 (GMP)	Lck
Aminogenistein	p56-Lck, IC₅₀: 1.2 μM
BMS-243117	Lck, IC₅₀: 4 nM	Fyn, IC₅₀: 32 nM	Blk, IC₅₀: 84 nM
SIK1-IN-1	Lck, IC₅₀: 3.7 nM			Fgr, IC₅₀: <3 nM	Hck, IC₅₀: <3 nM	Lyn, IC₅₀: <1.5 nM	Yes, IC₅₀: <3 nM

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