CAI/II-IN-5
CAI/II-IN-5 (compound MZ8) is a potent hCA I and hCA II (human carbonic anhydrase isoenzymes I and II) inhibitor, with IC50 values of 37.88 and 45.23 nM, respectively. CAI/II-IN-5 also shows inhibition profile against α-Glycosidase and AChE, with IC50 values of 48.98 and 420.14 nM, respectively. CAI/II-IN-5 can be used for the research of many diseases such as diabetes, Alzheimer’s disease, heart failure, ulcer, and epilepsy.
For research use only. We do not sell to patients.
- CAS No.: 2428389-67-5
- Formula: C21H18Cl2N8O4S2
- Molecular Weight:581.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CA I |
AChE |
CA Ⅱ |
Chemical Information
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CAS No. 2428389-67-5
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Molecular Weight 581.45
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Formula C21H18Cl2N8O4S2
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SMILES
ClC1=CC=C(NC2=NC(NC3=CC=C(S(=O)(N)=O)C=C3)=NC(NC4=CC=C(S(=O)(N)=O)C=C4)=N2)C=C1Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lolak N, et al. Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs. Bioorg Chem. 2020 Jul;100:103897. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CAI/II-IN-5 Related Classifications
HY-147955 Related Classifications
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