1. Cell Cycle/DNA Damage Apoptosis
  2. Topoisomerase Apoptosis
  3. Topoisomerase II inhibitor 15

Topoisomerase II inhibitor 15 (compound 2g) is a Topoisomerase II inhibitor. Topoisomerase II inhibitor 15 potently is an apoptotic inducer with greater selectivity against head and neck tumors.

For research use only. We do not sell to patients.

Topoisomerase II inhibitor 15 Chemical Structure

Topoisomerase II inhibitor 15 Chemical Structure

CAS No. : 451516-79-3

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Description

Topoisomerase II inhibitor 15 (compound 2g) is a Topoisomerase II inhibitor. Topoisomerase II inhibitor 15 potently is an apoptotic inducer with greater selectivity against head and neck tumors[1].

In Vitro

Topoisomerase II inhibitor 15 (compound 2g) shows very strong activities against HNO97 with IC50 values of 3 μg/mL. Topoisomerase II inhibitor 15 arrestes cell cycle progression at both the S and G2-M phases, as well as increased the early and late apoptosis phase ratios[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

332.19

Formula

C15H11Cl2N5

CAS No.
SMILES

ClC1=CC=C(C2N=C(N)N=C3NC4=C(N32)C=CC=C4)C=C1Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Topoisomerase II inhibitor 15 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Topoisomerase II inhibitor 15
Cat. No.:
HY-155645
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