2. Natural Products
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  4. Meliaceae

Meliaceae

 

Meliaceae (25):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19356
    Rocaglamide 84573-16-0 99.34%
    Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia.
    Rocaglamide
  • HY-N0263
    Toosendanin 58812-37-6 ≥98.0%
    Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb et Zucc, possesses analgesic, insecticidal and anti-inflammatory activities.
    Toosendanin
  • HY-Y1787
    Dimethyl malonate 108-59-8 99.92%
    Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis.
    Dimethyl malonate
  • HY-116035
    Nimbolide 25990-37-8 99.94%
    Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica). Nimbolide induces apoptosis through inactivation of NF-κB. Nimbolide inhibits CDK4/CDK6 kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways.
    Nimbolide
  • HY-126741
    Azadirachtin 11141-17-6 98.05%
    Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4.
    Azadirachtin
  • HY-N3396
    Laxiracemosin H 1241871-28-2
    Laxiracemosin H is a natural product that can be isolated from Dysoxylum laxiracemosum.
    Laxiracemosin H
  • HY-N3349
    Lyoniresinol 14464-90-5
    Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM.
    Lyoniresinol
  • HY-19355
    Rocagloic acid 190385-15-0 98.04%
    Rocagloic acid is a racaglamide derivative isolated from the fruits of Aglaia elliptifolia with potent cytotoxicity.
    Rocagloic acid
  • HY-15359
    Episilvestrol 697235-39-5 99.86%
    Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia perviridis, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity.
    Episilvestrol
  • HY-N1342
    Rocaglaol 147059-46-9
    Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells.
    Rocaglaol
  • HY-N1621
    1-Deacetylnimbolinin B 76689-98-0
    1-Deacetylnimbolinin B is a nimbolinin-type limonoid isolated from the fruits of Melia toosendan. Limonoids are a class of highly oxygenated nortriterpenoids that exhibit insecticidal, antifungal, nematicidal and cytotoxic properties.
    1-Deacetylnimbolinin B
  • HY-N1641
    1-O-Deacetylkhayanolide E 1007387-95-2
    1-O-Deacetylkhayanolide E is a khayanolide, which can be isolated from the stem bark of African mahogany Khaya senegalensis.
    1-O-Deacetylkhayanolide E
  • HY-N1640
    1-O-Deacetyl-2α-hydroxykhayanolide E 1189801-51-1
    1-O-Deacetyl-2α-hydroxykhayanolide E is a natural product that can be isolated from Swietenia mahagoni. 1-O-Deacetyl-2α-hydroxykhayanolide E is widely distributed in the leaves and branches of Swietenia mahagoni.
    1-O-Deacetyl-2α-hydroxykhayanolide E
  • HY-N5104
    Clemaphenol A 362606-60-8
    Clemaphenol A is a chemical constituent of the flower of Fritillaria pallidiflora.
    Clemaphenol A
  • HY-N10437
    6-Acetylnimbandiol 1281766-66-2
    6-Acetylnimbandiol (6-O-Acetylnimbandiol) is a non-cytotoxic tyrosinase inhibitor (IC50=69.85 μM) that effectively inhibits melanin production and MITF expression. 6-Acetylnimbandiol can be used in melanoma research.
    6-Acetylnimbandiol
  • HY-N1654
    2',3'-Dehydrosalannol 97411-50-2
    2',3'-Dehydrosalannol is a potent antibacterial agent. 2',3'-Dehydrosalannol shows antibacterial activity against K. pneumonia ATCC 13883, P. aeruginosa ATCC 27853, S. aureus ATCC 25922, E. coli ATCC 11775, and E. faecalis ATCC 10541, with MIC values of 0.78, 1.56, 1.56, 6.25, and 25 µg/mL, respectively.
    2',3'-Dehydrosalannol
  • HY-N7694
    Isotoosendanin 97871-44-8
    Isotoosendanin is a limonoid that can be isolated from Melia toosendan fruit. Isotoosendanin displays significant anti-inflammatory and analgesic activities.
    Isotoosendanin
  • HY-N4162
    3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone 1260173-73-6
    3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone is a cytotoxic tirucallane C26 triterpenoid isolated from the stem barks of Aphanamixis grandifolia.
    3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone
  • HY-N1317
    Salirepin 26652-12-0
    Salirepin is a phenolic glycoside from fruits of Idesia polycarpa, inhibits LPS-induced nitric oxide production.
    Salirepin
  • HY-W001251
    3,5-Dimethoxybenzoic acid 1132-21-4 99.66%
    3,5-Dimethoxybenzoic acid, isolated from Melia azedarach L. leaves with antifungal activity, is an intermediate in organic synthesis.
    3,5-Dimethoxybenzoic acid