2. Natural Products
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  4. Meliaceae

Meliaceae

 

Meliaceae (56):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19356
    Rocaglamide 84573-16-0 99.34%
    Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia.
    Rocaglamide
  • HY-N0263
    Toosendanin 58812-37-6 98.77%
    Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities.
    Toosendanin
  • HY-116035
    Nimbolide 25990-37-8 99.94%
    Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways.
    Nimbolide
  • HY-126741
    Azadirachtin 11141-17-6 99.06%
    Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4.
    Azadirachtin
  • HY-N7694
    Isotoosendanin 97871-44-8 98.92%
    Isotoosendanin is a limonoid that can be isolated from Melia toosendan fruit. Isotoosendanin displays significant anti-inflammatory and analgesic activities.
    Isotoosendanin
  • HY-124941
    7-Deacetylgedunin 10314-90-6
    7-Deacetylgedunin is an activator of Keap1/Nrf2/HO-1. 7-Deacetylgedunin alleviates mice mortality induced by LPS. 7-Deacetylgedunin inhibits Keap1 expression and suppresses macrophage proliferation. 7-Deacetylgedunin suppresses inflammation in vivo and in vitro.
    7-Deacetylgedunin
  • HY-N1687
    21,24-Epoxycycloartane-3,25-diol 125305-73-9
    21,24-Epoxycycloartane-3,25-diol (compound 15 or 16) is a cycloartanoid triterpene that can be isolated from the leaves of Lansium domesticum. 21,24-Epoxycycloartane-3,25-diol inhibits skin-tumor promotion.
    21,24-Epoxycycloartane-3,25-diol
  • HY-N3207
    Nemoralisin C 1443421-84-8
    Nemoralisin C is a chain-like diterpenoid, that can be isolated from the fruits of A. grandifolia.
    Nemoralisin C
  • HY-15359
    Episilvestrol 697235-39-5 99.86%
    Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia perviridis, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity.
    Episilvestrol
  • HY-N1342
    Rocaglaol 147059-46-9
    Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells.
    Rocaglaol
  • HY-W001251
    3,5-Dimethoxybenzoic acid 1132-21-4 99.66%
    3,5-Dimethoxybenzoic acid, isolated from Melia azedarach L. leaves with antifungal activity, is an intermediate in organic synthesis.
    3,5-Dimethoxybenzoic acid
  • HY-N1284
    Seneganolide 301530-12-1
    Seneganolide (compound 1) is isolated from the stem bark of Khaya senegalensis. Seneganolide can be used as insect antifeedant.
    Seneganolide
  • HY-156241
    Meliadubin B
    Meliadubin B is a natural triterpenoid with significant inflammatory inhibition effect toward superoxide anion generation in human neutrophils (EC50 of 5.54 μM). Meliadubin B inhibits inducible nitric oxide synthase. Meliadubin B shows remarkable inhibition against the rice pathogenic fungus Magnaporthe oryzae with IC50 of 182.50 μM.
    Meliadubin B
  • HY-N0957
    (±)-Pinoresinol 4263-88-1
    (±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity.
    (±)-Pinoresinol
  • HY-N10437
    6-Acetylnimbandiol 1281766-66-2
    6-Acetylnimbandiol (6-O-Acetylnimbandiol) is a non-cytotoxic tyrosinase inhibitor (IC50=69.85 μM) that effectively inhibits melanin production and MITF expression. 6-Acetylnimbandiol can be used in melanoma research.
    6-Acetylnimbandiol
  • HY-N10858
    Chisocheton compound F 157376-71-1
    Chisocheton compound F is a nature product that could be isolated from the stem bark of Melia toosendan.
    Chisocheton compound F
  • HY-N11079
    Toonaciliatin M 93930-04-2
    Toonaciliatin M (compound 6) is a pmaradiene-type diterpenoid that can be isolated from Toona ciliate. Toonaciliatin M show antifungal activity against Trichophyton rubrum with an MIC value of 12.5 µg/mL.
    Toonaciliatin M
  • HY-N1142
    Torachrysone 22649-04-3
    Torachrysone (Nakahalene; Trachrysone), a naphthalene, can be isolated from Cassia tora L.
    Torachrysone
  • HY-N11913
    Siderin 53377-54-1
    Siderin is a Photosystem II inhibitor that effectively inhibits ATP synthesis and chloroplast electron transport during photosynthesis in isolated spinach. Siderin can be used in the study of plant photosynthesis.
    Siderin
  • HY-N11958
    5-Hydroxy-3,6,7,4'-tetramethoxyflavone 14787-34-9
    5-Hydroxy-3,6,7,4'-tetramethoxyflavone is a natural compound isolated from Aglaia edulis.
    5-Hydroxy-3,6,7,4'-tetramethoxyflavone