5-Hydroxy-3,6,7,4'-tetramethoxyflavone
Based on 1 Customer Validation
5-Hydroxy-3,6,7,4'-tetramethoxyflavone is a natural compound isolated from Aglaia edulis.
For research use only. We do not sell to patients.
- Purity : 99.76%
- CAS No.: 14787-34-9
- Formula: C19H18O7
- Molecular Weight:358.34
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
>100 μM
Compound: 9
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Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT assay
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[PMID: 25659770] |
| HUVEC | ED50 |
>5 μg/mL
Compound: 5-hydroxy-3,6,7,4'-tetramethoxyflavone
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Cytotoxicity against HUVEC
Cytotoxicity against HUVEC
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[PMID: 17190457] |
| LNCaP | ED50 |
>5 μg/mL
Compound: 5-hydroxy-3,6,7,4'-tetramethoxyflavone
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Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
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[PMID: 17190457] |
| Lu1 | ED50 |
>5 μg/mL
Compound: 5-hydroxy-3,6,7,4'-tetramethoxyflavone
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Cytotoxicity against human Lu1 cells
Cytotoxicity against human Lu1 cells
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[PMID: 17190457] |
| MCF7 | ED50 |
>5 μg/mL
Compound: 5-hydroxy-3,6,7,4'-tetramethoxyflavone
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Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
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[PMID: 17190457] |
| Neutrophil | IC50 |
>10 μg/mL
Compound: 8
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Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced elastase release using Meo-Suc-Ala-Ala-Pro-Val-p-nitroanilide as substrate incubated for 5 mins prior to FMLP/CB-challenge by spectrophotometry
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced elastase release using Meo-Suc-Ala-Ala-Pro-Val-p-nitroanilide as substrate incubated for 5 mins prior to FMLP/CB-challenge by spectrophotometry
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[PMID: 22429052] |
| Neutrophil | IC50 |
>10 μg/mL
Compound: 8
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Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced superoxide-anion generation incubated for 5 mins prior to FMLP/CB-challenge measured after 10 mins by spectrophotometry
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced superoxide-anion generation incubated for 5 mins prior to FMLP/CB-challenge measured after 10 mins by spectrophotometry
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[PMID: 22429052] |
Chemical Information
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CAS No. 14787-34-9
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Appearance Solid
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Molecular Weight 358.34
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Formula C19H18O7
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Color White to off-white
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SMILES
O=C1C(OC)=C(C2=CC=C(OC)C=C2)OC3=CC(OC)=C(OC)C(O)=C13
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Hydroxy-3,6,7,4'-tetramethoxyflavone Related Classifications
HY-N11958 Related Classifications
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