2. Natural Products
  3. Plants
  4. Meliaceae

Meliaceae

 

Meliaceae (46):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19356
    Rocaglamide 84573-16-0 99.34%
    Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia.
    Rocaglamide
  • HY-N0263
    Toosendanin 58812-37-6 ≥98.0%
    Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities.
    Toosendanin
  • HY-Y1787
    Dimethyl malonate 108-59-8 99.92%
    Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis.
    Dimethyl malonate
  • HY-126741
    Azadirachtin 11141-17-6 99.06%
    Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4.
    Azadirachtin
  • HY-116035
    Nimbolide 25990-37-8 99.94%
    Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica). Nimbolide induces apoptosis through inactivation of NF-κB. Nimbolide inhibits CDK4/CDK6 kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways.
    Nimbolide
  • HY-N1142
    Torachrysone 22649-04-3
    Torachrysone (Nakahalene; Trachrysone), a naphthalene, can be isolated from Cassia tora L.
    Torachrysone
  • HY-N3801
    Eichlerianic acid 56421-13-7
    Eichlerianic acid is a natural product that can be isolated from Dysoxylum lenticellatum.
    Eichlerianic acid
  • HY-N0957
    (±)-Pinoresinol 4263-88-1
    (±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity.
    (±)-Pinoresinol
  • HY-19355
    Rocagloic acid 190385-15-0
    Rocagloic acid is a racaglamide derivative isolated from the fruits of Aglaia elliptifolia with potent cytotoxicity.
    Rocagloic acid
  • HY-15359
    Episilvestrol 697235-39-5 99.86%
    Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia perviridis, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity.
    Episilvestrol
  • HY-W001251
    3,5-Dimethoxybenzoic acid 1132-21-4 99.66%
    3,5-Dimethoxybenzoic acid, isolated from Melia azedarach L. leaves with antifungal activity, is an intermediate in organic synthesis.
    3,5-Dimethoxybenzoic acid
  • HY-N1342
    Rocaglaol 147059-46-9
    Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells.
    Rocaglaol
  • HY-N1317
    Salirepin 26652-12-0
    Salirepin is a phenolic glycoside from fruits of Idesia polycarpa, inhibits LPS-induced nitric oxide production.
    Salirepin
  • HY-N1621
    1-Deacetylnimbolinin B 76689-98-0
    1-Deacetylnimbolinin B is a nimbolinin-type limonoid isolated from the fruits of Melia toosendan. Limonoids are a class of highly oxygenated nortriterpenoids that exhibit insecticidal, antifungal, nematicidal and cytotoxic properties.
    1-Deacetylnimbolinin B
  • HY-N1640
    1-O-Deacetyl-2α-hydroxykhayanolide E 1189801-51-1
    1-O-Deacetyl-2α-hydroxykhayanolide E is a natural product that can be isolated from Swietenia mahagoni. 1-O-Deacetyl-2α-hydroxykhayanolide E is widely distributed in the leaves and branches of Swietenia mahagoni.
    1-O-Deacetyl-2α-hydroxykhayanolide E
  • HY-N1641
    1-O-Deacetylkhayanolide E 1007387-95-2
    1-O-Deacetylkhayanolide E is a khayanolide, which can be isolated from the stem bark of African mahogany Khaya senegalensis.
    1-O-Deacetylkhayanolide E
  • HY-N1654
    2',3'-Dehydrosalannol 97411-50-2
    2',3'-Dehydrosalannol is a potent antibacterial agent. 2',3'-Dehydrosalannol shows antibacterial activity against K. pneumonia ATCC 13883, P. aeruginosa ATCC 27853, S. aureus ATCC 25922, E. coli ATCC 11775, and E. faecalis ATCC 10541, with MIC values of 0.78, 1.56, 1.56, 6.25, and 25 µg/mL, respectively.
    2',3'-Dehydrosalannol
  • HY-N1710
    28-Deoxonimbolide 126005-94-5
    28-Deoxonimbolide is a nimbin (HY-N3187) type limonoid, that can be isolated from Azadirachta indica seed extracts. 28-Deoxonimbolide shows anticancer activity. 28-Deoxonimbolide induces apoptotic cell death in HL60 cells via both the mitochondrial- and the death receptor-mediated pathways.
    28-Deoxonimbolide
  • HY-N3349
    Lyoniresinol 14464-90-5
    Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM.
    Lyoniresinol
  • HY-N3694
    Deacetylnimbin 18609-16-0
    Deacetylnimbin is a limonoid isolated from Azadirachta indica. Deacetylnimbin can be used as a plant metabolite, a food repellent and as a growth regulator for insects such as S. litura, P. ricini and O. fscovittata.
    Deacetylnimbin