- Natural Products
- Plants
- Meliaceae
- Aglaia elliptifolia
Aglaia elliptifolia
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Aglaia elliptifolia (3)
- Formula: C29H31NO7
- Molecular Weight: 505.56
Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia.
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- Formula: C27H26O8
- Molecular Weight: 478.49
Rocagloic acid is a racaglamide derivative isolated from the fruits of Aglaia elliptifolia with potent cytotoxicity.
August 31
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- Formula: C25H34O5
- Molecular Weight: 414.53
20-Deoxyingenol 3-angelate (DI3A) increases degranulation and interferon-gamma secretion of NK cells. 20-Deoxyingenol 3-angelate enhances NK cell tumoricidal activity.
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