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  5. 20-Deoxyingenol 3-angelate

20-Deoxyingenol 3-angelate (DI3A) increases degranulation and interferon-gamma secretion of NK cells. 20-Deoxyingenol 3-angelate enhances NK cell tumoricidal activity.

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20-Deoxyingenol 3-angelate

20-Deoxyingenol 3-angelate Estructura química

No. CAS : 75567-38-3

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1 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
5 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
10 mg   Obtener un presupuesto  
50 mg   Obtener un presupuesto  
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Descripciòn

20-Deoxyingenol 3-angelate (DI3A) increases degranulation and interferon-gamma secretion of NK cells. 20-Deoxyingenol 3-angelate enhances NK cell tumoricidal activity[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
> 10 μM
Compound: 12
Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
HepG2 IC50
> 10 μM
Compound: 12
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
MT4 CC50
> 9.7 μM
Compound: 17
Cytotoxicity against human MT4 cells after 3 days by CytoTox-Glo assay
Cytotoxicity against human MT4 cells after 3 days by CytoTox-Glo assay
[PMID: 30031972]
PC-3 IC50
> 10 μM
Compound: 12
Cytotoxicity against human PC-3 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
SK-MEL-28 IC50
> 10 μM
Compound: 12
Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
Peso molecular

414.53

Fòrmula

C25H34O5

No. CAS
SMILES

O[C@@]12[C@]3(C=C([C@@H]2OC(/C(C)=C\C)=O)C)C([C@](C=C([C@H]1O)C)([H])[C@@]4([H])[C@@](C4(C)C)([H])C[C@H]3C)=O

Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Referencias
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
20-Deoxyingenol 3-angelate
Cat. No.:
HY-N1684
Cantidad:
MCE Japan Authorized Agent: