1. Acids and Aldehydes
  2. Rocagloic acid

Rocagloic acid 

Cat. No.: HY-19355 Purity: 98.04%
Handling Instructions

Rocagloic acid is a racaglamide derivative isolated from the fruits of Amoora cucullata with potent cytotoxicity.

For research use only. We do not sell to patients.

Rocagloic acid Chemical Structure

Rocagloic acid Chemical Structure

CAS No. : 190385-15-0

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 400 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 400 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 380 In-stock
Estimated Time of Arrival: December 31
10 mg USD 650 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Rocagloic acid is a racaglamide derivative isolated from the fruits of Amoora cucullata with potent cytotoxicity[1].

In Vitro

Rocagloic acid shows selective cytotoxicity against NCI-H187 cell line with an ED50 of 0.036 ng/mL, and is inactive against oral human epidermoid carcinoma (KB) and human breast cancer (BC) cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

478.49

Formula

C₂₇H₂₆O₈

CAS No.
SMILES

O=C([[email protected]]([[email protected]]1C2=CC=CC=C2)[[email protected]@H](O)[[email protected]]3(O)[[email protected]@]1(C4=CC=C(OC)C=C4)OC5=CC(OC)=CC(OC)=C35)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (417.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0899 mL 10.4495 mL 20.8991 mL
5 mM 0.4180 mL 2.0899 mL 4.1798 mL
10 mM 0.2090 mL 1.0450 mL 2.0899 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5 mg/mL (10.45 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 5 mg/mL (10.45 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5 mg/mL (10.45 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

Rocagloic acidOthersCytotoxicityracaglamidederivativeInhibitorinhibitorinhibit

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Product Name:
Rocagloic acid
Cat. No.:
HY-19355
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