2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Spermidine-d6

Spermidine-d6 is the deuterium labeled Spermidine[1]. Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents[2].

For research use only. We do not sell to patients.

Spermidine-d<sub>6</sub> Chemical Structure

Spermidine-d6 Chemical Structure

CAS No. : 2514812-10-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Spermidine-d6:

Spermidine-d6 Related Antibodies

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Description

Spermidine-d6 is the deuterium labeled Spermidine[1]. Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Spermidine-d6 Related Antibodies
Molecular Weight

151.28

Formula

C7H13D6N3
CAS No.
Appearance

Liquid

Color

Colorless to off-white

SMILES

NC([2H])([2H])C([2H])([2H])C([2H])([2H])NCCCCN
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (661.03 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.6103 mL 33.0513 mL 66.1026 mL
5 mM 1.3221 mL 6.6103 mL 13.2205 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 96.07%

COA (244 KB) HNMR (807 KB) RP-HPLC (761 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.6103 mL 33.0513 mL 66.1026 mL 165.2565 mL
5 mM 1.3221 mL 6.6103 mL 13.2205 mL 33.0513 mL
10 mM 0.6610 mL 3.3051 mL 6.6103 mL 16.5256 mL
15 mM 0.4407 mL 2.2034 mL 4.4068 mL 11.0171 mL
20 mM 0.3305 mL 1.6526 mL 3.3051 mL 8.2628 mL
25 mM 0.2644 mL 1.3221 mL 2.6441 mL 6.6103 mL
30 mM 0.2203 mL 1.1017 mL 2.2034 mL 5.5085 mL
40 mM 0.1653 mL 0.8263 mL 1.6526 mL 4.1314 mL
50 mM 0.1322 mL 0.6610 mL 1.3221 mL 3.3051 mL
60 mM 0.1102 mL 0.5509 mL 1.1017 mL 2.7543 mL
80 mM 0.0826 mL 0.4131 mL 0.8263 mL 2.0657 mL
100 mM 0.0661 mL 0.3305 mL 0.6610 mL 1.6526 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Spermidine-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Spermidine-d62514812-10-1Endogenous MetaboliteInhibitorinhibitorinhibit

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