hCAI/II-IN-1
hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor with IC50 values of 0.047 µM and 0.024 µM against hCA I and hCA II, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2422028-82-6
- Formula: C18H29N5O3S3
- Molecular Weight:459.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.024 µM (hCA II), 0.047 µM (hCA I)[1]
Ki: 0.013 µM (hCA II), 0.032 µM (hCA I)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
>1000 μM
Compound: 3h
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Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
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[PMID: 32388113] |
Chemical Information
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CAS No. 2422028-82-6
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Molecular Weight 459.65
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Formula C18H29N5O3S3
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SMILES
CN(CCCN1CCN(CC1)C(SCC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)=S)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hCAI/II-IN-1 Related Classifications
HY-146385 Related Classifications
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