2. Anti-infection
  3. HIV
  4. HIV-1 inhibitor-18

HIV-1 inhibitor-18 (compound II-13c) is a potent HIV-1 capsid inhibitor with an EC50 value of 5.14 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >9.51).

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HIV-1 inhibitor-18

HIV-1 inhibitor-18 Estructura química

No. CAS : 2764787-56-4

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HIV-1 inhibitor-18 Related Antibodies

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Descripciòn

HIV-1 inhibitor-18 (compound II-13c) is a potent HIV-1 capsid inhibitor with an EC50 value of 5.14 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >9.51)[1].

IC50 & Target[1]

HIV-1 NL4-3

5.14 μM (EC50)

Cellular Effect
Cell Line Type Value Description References
MT4 CC50
> 9.51 μM
Compound: II-13c
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 3 days by XTT assay
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 3 days by XTT assay
[PMID: 34562701]
Peso molecular

525.62

Fòrmula

C27H31N3O6S
No. CAS
SMILES

O=C(N(C1=CC=C(OC)C=C1)C)[C@@H](NS(=O)(CC(N(C2=CC=C(OC)C=C2)C)=O)=O)CC3=CC=CC=C3
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Room temperature in continental US; may vary elsewhere.
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Referencias
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HIV-1 inhibitor-18 Related Classifications

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Keywords:

HIV-1 inhibitor-182764787-56-4HIVHuman immunodeficiency virusCapsidAnti-HIVAIDSMT-4 cellsInhibitorinhibitorinhibit

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Nombre del producto:
HIV-1 inhibitor-18
Cat. No.:
HY-144714
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