1. Anti-infection
  2. HIV
  3. HIV-1 inhibitor-18

HIV-1 inhibitor-18 (compound II-13c) is a potent HIV-1 capsid inhibitor with an EC50 value of 5.14 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >9.51).

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HIV-1 inhibitor-18 Chemical Structure

HIV-1 inhibitor-18 Chemical Structure

CAS No. : 2764787-56-4

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Description

HIV-1 inhibitor-18 (compound II-13c) is a potent HIV-1 capsid inhibitor with an EC50 value of 5.14 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >9.51)[1].

IC50 & Target[1]

HIV-1 NL4-3

5.14 μM (EC50)

Molecular Weight

525.62

Formula

C27H31N3O6S

CAS No.
SMILES

O=C(N(C1=CC=C(OC)C=C1)C)[C@@H](NS(=O)(CC(N(C2=CC=C(OC)C=C2)C)=O)=O)CC3=CC=CC=C3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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HIV-1 inhibitor-18 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HIV-1 inhibitor-18
Cat. No.:
HY-144714
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