HIV-1 inhibitor-18
HIV-1 inhibitor-18 (compound II-13c) is a potent HIV-1 capsid inhibitor with an EC50 value of 5.14 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >9.51).
For research use only. We do not sell to patients.
- CAS No.: 2764787-56-4
- Formula: C27H31N3O6S
- Molecular Weight:525.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HIV-1 NL4-3 5.14 μM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
>9.51 μM
Compound: II-13c
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Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 3 days by XTT assay
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 3 days by XTT assay
|
[PMID: 34562701] |
Chemical Information
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CAS No. 2764787-56-4
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Molecular Weight 525.62
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Formula C27H31N3O6S
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SMILES
O=C(N(C1=CC=C(OC)C=C1)C)[C@@H](NS(=O)(CC(N(C2=CC=C(OC)C=C2)C)=O)=O)CC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)