ALDH1A2 Antibody (YA1469)
(Synonyms: ALDH1A2; RALDH2; Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II))ALDH1A2 Antibody (YA1469) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ALDH1A2.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
ALDH1A2 Antibody (YA1469) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ALDH1A2.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 57 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 57 kDa
Entrez Gene: 8854 Human ; 19378 Mouse ; 116676 Rat
SwissProt: O94788 Human ; Q62148 Mouse ; Q63639 Rat
OMIM: 620025 Human
A synthesized peptide derived from human ALDH1A2 aa5-50.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
ALDH1A2 catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. Retinoate signaling is critical for the transcriptional control of many genes, for instance it is crucial for initiation of meiosis in both male and female (Probable). Recognizes retinal as substrate, both in its free form and when bound to cellular retinol-binding protein. Can metabolize octanal and decanal, but has only very low activity with benzaldehyde, acetaldehyde and propanal. Displays complete lack of activity with citral[1][2].
-
Subcellular Localization
Cytoplasm
-
Isoforms & Post-Translational Modification
O94788 has 4 isomers: O94788-1: 56724 Da (predicted); O94788-2: 53060 Da (predicted); O94788-3: 54673 Da (predicted); O94788-4: 46137 Da (predicted).
-
Subunit
Homotetramer
-
SwissProt ID
-
Synonyms
ALDH1A2; RALDH2; Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II)
-
Research Field
Neuroscience
Documentation
Powered by Bioz
