1. PI3K/Akt/mTOR
  2. mTOR
  3. Rheb inhibitor NR1

Rheb inhibitor NR1 

Cat. No.: HY-124798
Handling Instructions

Rheb inhibitor NR1 is a Rheb inhibitor with an IC50 of 2.1 µM in the Rheb-IVK assay. Rheb inhibitor NR1 also is a selective mTORC1 inhibitor. NR1 inhibits the phosphorylation of T389pS6K1 and increases the phosphorylation of S473pAKT in a dose-dependent manner.

For research use only. We do not sell to patients.

Rheb inhibitor NR1 Chemical Structure

Rheb inhibitor NR1 Chemical Structure

CAS No. : 2216763-38-9

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Description

Rheb inhibitor NR1 is a Rheb inhibitor with an IC50 of 2.1 µM in the Rheb-IVK assay. Rheb inhibitor NR1 also is a selective mTORC1 inhibitor. NR1 inhibits the phosphorylation of T389pS6K1 and increases the phosphorylation of S473pAKT in a dose-dependent manner[1].

Molecular Weight

578.30

Formula

C₂₅H₁₉BrCl₂N₂O₃S

CAS No.

2216763-38-9

SMILES

O=C(C(N1CC2=CC=C(C(N(C)C)=O)C=C2)=CC3=C1C=C(SC4=CC=C(Cl)C(Cl)=C4)C=C3Br)O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Rheb inhibitor NR1Rheb inhibitor NR 1Rheb inhibitor NR-1mTORMammalian target of RapamycinInhibitorinhibitorinhibit

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Rheb inhibitor NR1
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HY-124798
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