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Cat. No.: HY-155693

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Topoisomerase II inhibitor 16

Name: Topoisomerase II inhibitor 16
Brand: MedChemExpress
SKU: HY-155693
Price: 87.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research.

For research use only. We do not sell to patients.

CAS No.: 2403729-27-9
Formula: C₁₉H₁₂F₄N₆O
Molecular Weight:416.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Topoisomerase II inhibitor 16 Chemical Structure

CAS No.: 2403729-27-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Topoisomerase Isoforms :

All Parasite Isoforms :

Chemical Information

CAS No. 2403729-27-9
Molecular Weight 416.33
Formula C₁₉H₁₂F₄N₆O
SMILES

FC(F)(F)C1=C(C2=CC=C(CN(C(CN3C=NC(C#N)=N3)=O)C4)C4=C2)C=C(F)C=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Srinivasa P S Rao, et al. Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science. 2023 Jun 30;380(6652):1349-1356. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Topoisomerase II inhibitor 16

All Topoisomerase Isoforms

All Parasite Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Topoisomerase II inhibitor 16 Related Classifications

HY-155693 Related Classifications

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