2403729-27-9
2403729-27-9
Chemical Structure
Topoisomerase II inhibitor 16
- CAS. Nr.: 2403729-27-9
- Formula:C19H12F4N6O
- Molecular Weight:416.33
InChIKey: JDTWUDDOSHJEIZ-UHFFFAOYSA-N
SMILES: FC(F)(F)C1=C(C2=CC=C(CN(C(CN3C=NC(C#N)=N3)=O)C4)C4=C2)C=C(F)C=N1
Biological Activity: Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research[1].
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Topoisomerase II inhibitor 16 | Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research. | |||||||||||||||||||||
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