1. Cell Cycle/DNA Damage
    Antibody-drug Conjugate/ADC Related
  2. Topoisomerase
    ADC Cytotoxin
  3. MC-DOXHZN hydrochloride

MC-DOXHZN hydrochloride (Synonyms: Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride)

Cat. No.: HY-16261B
Handling Instructions

MC-DOXHZN hydrochloride is an albumin-binding prodrug of Doxorubicin, with acid-sensitive properties.

For research use only. We do not sell to patients.

MC-DOXHZN hydrochloride Chemical Structure

MC-DOXHZN hydrochloride Chemical Structure

CAS No. : 480998-12-7

Size Price Stock
5 mg USD 70 Get quote
10 mg USD 100 Get quote
50 mg USD 280 Get quote
100 mg USD 450 Get quote

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Other In-stock Forms of MC-DOXHZN hydrochloride:

Other Forms of MC-DOXHZN hydrochloride:

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  • Technical Information

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  • References

Description

MC-DOXHZN hydrochloride is an albumin-binding prodrug of Doxorubicin, with acid-sensitive properties[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (158.79 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2703 mL 6.3515 mL 12.7031 mL
5 mM 0.2541 mL 1.2703 mL 2.5406 mL
10 mM 0.1270 mL 0.6352 mL 1.2703 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (2.64 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (2.64 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

787.21

Formula

C₃₇H₄₃ClN₄O₁₃

CAS No.

480998-12-7

SMILES

[H][[email protected]@]1(O[[email protected]]2C[[email protected]@](/C(CO)=N\NC(CCCCCN3C(C=CC3=O)=O)=O)(O)CC(C2=C4O)=C(O)C5=C4C(C6=C(OC)C=CC=C6C5=O)=O)O[[email protected]@H](C)[[email protected]@H](O)[[email protected]@H](N)C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
MC-DOXHZN hydrochloride
Cat. No.:
HY-16261B
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MC-DOXHZN hydrochloride

Cat. No.: HY-16261B