1. Signaling Pathways
  2. Antibody-drug Conjugate/ADC Related
  3. ADC Cytotoxin
  4. Maytansinoids Isoform

Maytansinoids

 

Maytansinoids Related Products (11):

Cat. No. Product Name Effect Purity
  • HY-19792
    Mertansine
    99.80%
    Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.
  • HY-15739
    Ansamitocin P-3
    ≥98.0%
    Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor.
  • HY-19474
    Maytansinol
    99.56%
    Maytansinol inhibits microtubule assembly and induces microtubule disassembly in vitro.
  • HY-130082
    DM4-SMe
    ≥98.0%
    DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond.
  • HY-130080
    DM3
    DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs).
  • HY-19839
    Ansamitocin P 3'
    Ansamitocin P 3' exhibits antitumour activity, is an antibody drug conjugate cytotoxin.
  • HY-130081
    DM3-SMe
    DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond.
  • HY-100504
    S-methyl DM1
    S-methyl DM1 is a thiomethyl derivative of Maytansine.
  • HY-100503
    Maytansinoid DM4
    Maytansinoid DM4 is a thiol-containing maytansine derivative with highly potent cytotoxicity.
  • HY-100128
    DM1-SMe
    DM1-SMe is an unconjugated form of the Maytansinoid in IMGN901.
  • HY-126663
    N-Me-L-Ala-maytansinol
    N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used for making antibody-drug conjugate (ADC).