1. Antibody-drug Conjugate/ADC Related
    Cytoskeleton
    Cell Cycle/DNA Damage
  2. ADC Cytotoxin
    Microtubule/Tubulin
  3. DM3

DM3 (Synonyms: Maytansinoid DM3)

Cat. No.: HY-130080
Handling Instructions

DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

DM3 Chemical Structure

DM3 Chemical Structure

CAS No. : 796073-54-6

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Description

DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Maytansinoids

 

Molecular Weight

766.34

Formula

C₃₇H₅₂ClN₃O₁₀S

CAS No.

796073-54-6

SMILES

C[[email protected]]12[[email protected]]([[email protected]@H]([[email protected]](O3)([H])C[[email protected]]([[email protected]](/C=C/C=C(C)/CC4=CC(N(C)C(C[[email protected]]2([H])OC([[email protected]](C)N(C)C(CCC(S)C)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

DM3Maytansinoid DM3DM 3DM-3Maytansinoid DM 3Maytansinoid DM-3ADC CytotoxinMicrotubule/TubulinInhibitorinhibitorinhibit

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