2. Signaling Pathways
  3. Antibody-drug Conjugate/ADC Related
  4. ADC Cytotoxin
  5. Traditional Cytotoxic Agents Isoform

Traditional Cytotoxic Agents

 

Traditional Cytotoxic Agents Related Products (26):

Cat. No. Product Name Effect Purity
  • HY-B0015
    Paclitaxel
    		99.97%
    Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization.
  • HY-14519
    Methotrexate
    		99.75%
    Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
  • HY-19610
    α-Amanitin
    		99.92%
    α-Amanitin is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II.
  • HY-15584
    Taltobulin
    		99.90%
    Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
  • HY-14519A
    Methotrexate disodium
    		99.71%
    Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
  • HY-15584B
    Taltobulin hydrochloride
    		98.34%
    Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
  • HY-125586
    β-Amanitin
    β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom.
  • HY-20584
    10-Deacetyl-7-xylosyl paclitaxel
    		99.65%
    10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel (a microtubule stabilizing agent; enhances tubulin polymerization) derivative with improved pharmacological features.
  • HY-15584A
    Taltobulin trifluoroacetate
    		99.96%
    Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
  • HY-100861
    C-11
    C-11 is a tubulin inhibitor and acts as an ADC cytotoxin, displays cytotoxicity for carcinoma cell lines.
  • HY-14519D
    Methotrexate monohydrate
    Methotrexate (Amethopterin) monohydrate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
  • HY-15995
    Tubulysin A
    Tubulysin A(TubA) is a myxobacterial product that can function as an antiangiogenic agent in many in vitro assays; anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative.
  • HY-19825
    Rebeccamycin
    Rebeccamycin, an antitumor antibiotic, inhibits DNA topoisomerase I.
  • HY-19826
    Isofistularin-3
    Isofistularin-3 is a direct, DNA-competitive DNMT1 inhibitor, with an IC50 of 13.5 μM.
  • HY-131081
    γ-Amanitin
    γ-Amanitin an ADC cytotoxin and isolated from the mushroom.
  • HY-131083
    ε-Amanitin
    ε-Amanitin, a cyclic peptide isolated from a variety of mushroom species, potently binds to and inhibits the activity of RNA polymerase II.
  • HY-122534
    Mensacarcin
    Mensacarcin, a highly complex polyketide, strongly inhibits cell growth universally in cancer cell lines and potently induces apoptosis in melanoma cells.
  • HY-130959
    Tubulysin IM-2
    Tubulysin IM-2 is an ADC Cytotoxin and tubulin binder used as anti-microtubule toxins.
  • HY-130960
    Tubulysin IM-3
    Tubulysin IM-3 is an ADC Cytotoxin and tubulin binder used as anti-microtubule toxins.
  • HY-133570
    17-AEP-GA
    17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.