17-AEP-GA
17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin.
For research use only. We do not sell to patients.
- CAS No.: 75747-23-8
- Formula: C34H50N4O8
- Molecular Weight:642.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
HSP90 |
Traditional Cytotoxic Agents |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| SK-BR-3 | IC50 |
70 nM
Compound: 1g
|
Cytotoxicity against human SKBR3 cells after 72 hrs by celltiter-glo assay
Cytotoxicity against human SKBR3 cells after 72 hrs by celltiter-glo assay
|
[PMID: 19405528] |
Chemical Information
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CAS No. 75747-23-8
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Molecular Weight 642.78
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Formula C34H50N4O8
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SMILES
O=C(C(NCCN1CCCC1)=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(C)\C3=O)C=C(N3)C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)