1. Signaling Pathways
  2. Antibody-drug Conjugate/ADC Related
  3. ADC Cytotoxin
  4. Duocarmycins Isoform

Duocarmycins

 

Duocarmycins Related Products (18):

Cat. No. Product Name Effect Purity
  • HY-107769
    Duocarmycin TM
    98.87%
    Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic.
  • HY-129379
    DC0-NH2
    DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability.
  • HY-112898
    DC1SMe
    ≥98.0%
    DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively.
  • HY-129355
    Duocarmycin Analog
    Duocarmycin Analog is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin.
  • HY-12455
    Duocarmycin A
    Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA.
  • HY-112900
    DC41SMe
    DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC50s ranging from 18-25 pM.
  • HY-112901
    DC41
    DC41 is a DC1 derivative.
  • HY-130083
    Seco-Duocarmycin TM
    Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis.
  • HY-12456
    Duocarmycin SA
    Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM.
  • HY-135122
    DC10SMe
    DC10SMe is a DNA alkylator, can be used in the synthesis of Antibody-drug Conjugate (ADC).
  • HY-112899
    DC1
    DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin.
  • HY-128880
    (+)-CBI-CDPI1
    (+)-CBI-CDPI1 is an enhanced functional analog of CC-1065.
  • HY-129356
    Seco-Duocarmycin SA
    Seco-Duocarmycin SA is a DNA alkylator, and is used as an ADC cytotoxin.
  • HY-128881
    (+)-CBI-CDPI2
    (+)-CBI-CDPI2 is an enhanced functional analog of CC-1065.
  • HY-107770
    Duocarmycin MB
    Duocarmycin MB is an antibody drug conjugates (ADCs) toxin.
  • HY-135123
    DC4SMe
    DC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC).
  • HY-18987
    Duocarmycin MA
    Duocarmycin MA is an antibody drug conjugates (ADCs) toxin.
  • HY-128873
    Duocarmycin GA
    Duocarmycin GA is an antibody drug conjugates (ADCs) toxin.