1. Antibody-drug Conjugate/ADC Related
  2. ADC Cytotoxin
  3. Duocarmycin SA

Duocarmycin SA 

Cat. No.: HY-12456
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Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro.

For research use only. We do not sell to patients.

Duocarmycin SA Chemical Structure

Duocarmycin SA Chemical Structure

CAS No. : 130288-24-3

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Description

Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM[1]. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro[2].

Molecular Weight

477.47

Formula

C₂₅H₂₃N₃O₇

CAS No.

130288-24-3

SMILES

O=C(C(N1)=CC([[email protected]@]23[[email protected]@](C3)([H])CN(C(C(N4)=CC5=C4C(OC)=C(OC)C(OC)=C5)=O)C2=C6)=C1C6=O)OC

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Duocarmycin SA
Cat. No.:
HY-12456
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