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Cat. No.: HY-128881

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(+)-CBI-CDPI2

(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody agent conjugates (ADCs) toxin.

For research use only. We do not sell to patients.

CAS No.: 128300-15-2
Formula: C₃₆H₂₈N₆O₄
Molecular Weight:608.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

(+)-CBI-CDPI2 Chemical Structure

CAS No.: 128300-15-2

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody agent conjugates (ADCs) toxin.

IC₅₀ & Target

Duocarmycins

All ADC Payloads Isoforms :

Chemical Information

CAS No. 128300-15-2
Molecular Weight 608.65
Formula C₃₆H₂₈N₆O₄
SMILES

O=C(N1C2=CC=C3NC(C(N4C5=CC=C6NC(C(N7C[C@](C8)([H])[C@]98C%10=CC=CC=C%10C(C=C79)=O)=O)=CC6=C5CC4)=O)=CC3=C2CC1)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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(+)-CBI-CDPI2

All ADC Payloads Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(+)-CBI-CDPI2 Related Classifications

HY-128881 Related Classifications