1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin

Podophyllotoxin (Synonyms: Podofilox; PPT)

Cat. No.: HY-15552
Handling Instructions

Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II.

For research use only. We do not sell to patients.
Podophyllotoxin Chemical Structure

Podophyllotoxin Chemical Structure

CAS No. : 518-28-5

Size Price Stock Quantity
Free sample   Apply now  
10 mM * 1 mL in DMSO $55 In-stock
100 mg $50 In-stock
500 mg $70 In-stock
1 g   Get quote  
5 g   Get quote  

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Description

Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. IC50 Value: Target: Topoisomerase II; Microtubule/Tubulin Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use.

Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.4131 mL 12.0653 mL 24.1307 mL
5 mM 0.4826 mL 2.4131 mL 4.8261 mL
10 mM 0.2413 mL 1.2065 mL 2.4131 mL
M.Wt

414.41

Formula

C₂₂H₂₂O₈

CAS No.

518-28-5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

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Podophyllotoxin
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