1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin

Podophyllotoxin (Synonyms: Podofilox; PPT)

Cat. No.: HY-15552 Purity: 98.16%
Data Sheet SDS Handling Instructions

Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II.

For research use only. We do not sell to patients.
Podophyllotoxin Chemical Structure

Podophyllotoxin Chemical Structure

CAS No. : 518-28-5

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10 mM * 1 mL in DMSO $55 In-stock
100 mg $50 In-stock
500 mg $70 In-stock
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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. IC50 Value: Target: Topoisomerase II; Microtubule/Tubulin Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use.

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References
Molecular Weight

414.41

Formula

C₂₂H₂₂O₈

CAS No.

518-28-5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Podophyllotoxin
Cat. No.:
HY-15552
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