Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from Scleria striatinux with antiplasmodial activity

  • J Nat Prod. 2009 Feb 27;72(2):280-3. doi: 10.1021/np800338p.
Simon M N Efange  1 ,  Reto Brun ,  Sergio Wittlin ,  Joseph D Connolly ,  Thomas R Hoye ,  Thomas McAkam ,  Felix L Makolo ,  James A Mbah ,  Dorian P Nelson ,  Kennedy D Nyongbela ,  Clare K Wirmum
Affiliations
  • 1. Department of Chemistry, University of Buea, PO Box 63, Buea, Southwest Province, Cameroon. [email protected]
PMID: 19199815 DOI: 10.1021/np800338p
Abstract

Okundoperoxide (1) was isolated by bioassay-guided fractionation of extracts from Scleria striatinux (syn. S. striatonux). The compound contains a cyclic endoperoxide structural moiety and possesses moderate antimalarial activity.