Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii

  • J Nat Prod. 2007 Oct;70(10):1565-9. doi: 10.1021/np0702133.
Martin Senn  1 ,  Sigmund Gunzenhauser ,  Reto Brun ,  Urs Séquin
Affiliations
  • 1. Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH-4056 Basel, Switzerland.
PMID: 17922552 DOI: 10.1021/np0702133
Abstract

From the petroleum ether extract of the root bark of Cussonia zimmermannii four polyacetylenes, 1- 4, were isolated, three of which ( 1- 3) were active against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Plasmodium falciparum, and Leishmania donovani.