1. Natural Products
  2. Phenylpropanoids
  3. Lignans

Lignans

Lignans (125):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-13629
    Etoposide 33419-42-0 99.86%
    Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy.
    Etoposide
  • HY-N0003
    Honokiol 35354-74-6 98.92%
    Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier.
    Honokiol
  • HY-15494
    Picropodophyllin 477-47-4 99.90%
    Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
    Picropodophyllin
  • HY-N0198
    Nordihydroguaiaretic acid 500-38-9 99.88%
    Nordihydroguaiaretic acid is a 5-lipoxygenase (5LOX) (IC50=8 μM) and tyrosine kinase inhibitor.
    Nordihydroguaiaretic acid
  • HY-N0035
    Arctigenin 7770-78-7 99.69%
    Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions.
    Arctigenin
  • HY-N10110
    (±)-Phrymarolin II 23720-86-7
    (±)-Phrymarolin II is a promising new class of plant virus (tobacco mosaic virus) inhibitors.
    (±)-Phrymarolin II
  • HY-N0089
    Schisandrin B 61281-37-6 99.86%
    Schisandrin B (γ-Schisandrin) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae, has been shown to produce antioxidant effect on rodent liver and heart.
    Schisandrin B
  • HY-15552
    Podofilox 518-28-5 99.92%
    Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II.
    Podofilox
  • HY-N0163
    Magnolol 528-43-8 99.92%
    Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis, is a dual agonist of both RXRα and PPARγ, with EC50 values of 10.4 µM and 17.7 µM, respectively.
    Magnolol
  • HY-N0121
    Sesamin 607-80-7 99.70%
    Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia.
    Sesamin
  • HY-N0693
    Schisandrin A 61281-38-7 99.43%
    Schisandrin A inhibits CYP3A activity with an IC50 of 6.60 μM and Ki of 5.83 μM, respectively.
    Schisandrin A
  • HY-N0482
    Phillyrin 487-41-2 98.99%
    Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities. Phillyrin has anti-influenza A virus activities.
    Phillyrin
  • HY-N0692
    Schisandrol B 58546-54-6 99.57%
    Schisandrol B (Gomisin-A) is a major active constituent of Schisandra sphenanthera with hepato-protective effects. Schisandrol B inhibits reactive oxygen species (ROS) production. Schisandrol B inhibits the activity of P-glycoprotein and CYP3A and also has anti-inflammatory, anti-diabetic and antioxidant activities.
    Schisandrol B
  • HY-N1374
    Magnolin 31008-18-1 99.98%
    Magnolin, a major component of Magnolia flos (Shin-Yi), inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.
    Magnolin
  • HY-105008
    Secoisolariciresinol diglucoside 257930-74-8 99.94%
    Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects.
    Secoisolariciresinol diglucoside
  • HY-N0691
    Schisandrin 7432-28-2 99.51%
    Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats.
    Schisandrin
  • HY-N0694
    Schisantherin A 58546-56-8 99.43%
    Schisantherin A is a dibenzocyclooctadiene lignan. Schisantherin A inhibits p65-NF-κB translocation into the nucleus by IκBα degradation.
    Schisantherin A
  • HY-N0385
    Gomisin J 66280-25-9 99.67%
    Gomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. gomisin J has potential benefits in treating nonalcoholic fatty liver disease.
    Gomisin J
  • HY-N0657
    Pinoresinol Diglucoside 63902-38-5 ≥98.0%
    Pinoresinol Diglucoside is one of the major lignans with various pharmacological activities which could be isolated from Duzhong and other plant species.
    Pinoresinol Diglucoside
  • HY-N0701
    (-)-Asarinin 133-04-0 ≥99.0%
    (-)-Asarinin is a extract lignan from Zanthoxylum armatum, mainly produced in roots of this herb[1].
    (-)-Asarinin